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  • Book
    [edited by] Daniel J. Berry, William J. Maloney.
    Contents:
    pt. I Surgical Approaches
    ch. 1 Anterior Approach Total Hip Arthroplasty / Michael Taunton
    ch. 2 The Direct Lateral Approach for Total Hip Arthroplasty / Stuart B. Goodman
    ch. 3 Posterolateral Approach (Including Minimally Invasive Variations) / James I. Huddleston
    ch. 4 Conventional Trochanteric Osteotomies and the Trochanteric Slide / Andrew H. Glassman
    pt. II Nonarthroplasty Approaches
    ch. 5 Extended Trochanteric Osteotomy / Wayne G. Paprosky
    ch. 6 Hip Arthroscopy for Nonstructural Pathology / Elizabeth Ford
    ch. 7 Arthroscopy for Structural Hip Problems / Bruce A. Levy
    ch. 8 Head-Sparing Procedures for Osteonecrosis of the Femoral Head / Michael A. Mont
    ch. 9 Periacetabular Osteotomy and Femoral Osteotomy / John C. Clohisy
    ch. 10 Hip Arthrodesis / Clive Duncan
    pt. III Primary Total Hip Arthroplasty
    ch. 11 Principles, Planning, and Decision Making / Young-Min Kwon
    ch. 12 Cemented Acetabular Component in Total Hip Arthroplasty / Andrew John Timperley
    ch. 13 The Uncemented Socket / John C. Clohisy
    ch. 14 The Polished Tapered Cemented Stem / Jonathan R. Howell
    ch. 15 Extensively Coated Stems / C. Anderson Engh Jr.
    ch. 16 The Tapered Stem / William J. Hozack
    ch. 17 Double-Tapered Primary Stems / Thomas P. Schmalzried
    ch. 18 Modular Stems / David A. Mattingly
    pt. IV Complex Primary Total Hip Arthroplasty
    ch. 19 Techniques for DDH Cup and Femur / Steven J. MacDonald
    ch. 20 Total Hip Arthroplasty in Patients with Proximal Femoral Deformity / Daniel J. Berry
    pt. V Revision Total Hip Arthroplasty
    ch. 21 Principles, Planning, and Decision Making / Nicholas J. Giori
    ch. 22 Component Removal / Rafael J. Sierra
    ch. 23 Uncemented Acetabular Revision with Hemispherical Cups / Erdan Kayupov
    ch. 24 Uncemented Acetabular Revision with Metal Augments or Cup-Cage Combinations / David G. Lewallen
    ch. 25 Custom Triflanged Devices in the Revision Acetabulum / Douglas A. Dennis
    ch. 26 Cemented Stems, Impaction Grafting, and Cement in Cement Revision / Donald William Howie
    ch. 27 Extensively Porous-Coated Cylindrical Uncemented Femoral Stems / Scott M. Sporer
    ch. 28 Tapered Fluted Titanium Stems in Revision Total Hip Arthroplasty / Donald S. Garbuz
    ch. 29 Allograft Prosthetic Composite and Endoprosthetic Replacement of the Proximal Femur / Chris Beauchamp
    pt. VI Special Revision Techniques
    ch. 30 Techniques to Manage Infection around Total Hip Arthroplasty and Antibiotic-Loaded Spacers for Infection / Bassam A. Masri
    ch. 31 Techniques to Manage Osteolysis Around Well-Fixed Acetabular Components / William J. Maloney.
    Digital Access
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    Version
    Ovid
    LWW Health Library
  • Article
    Johnsen K, Molin S, Karlström O, Maaloe O.
    J Bacteriol. 1977 Jul;131(1):18-29.
    The energy source shift-down described in the preceding paper (Molin et al., J. Bacteriol. 131: 7-17, 1977) was used to study the effects of shift-down on protein synthesis. The overall rate of protein synthesis was reduced immediately, and to the same extent, in stringent and relaxed strains. The primary effect of the shift was a slowing down of the polypeptide chain growth rate, a finding not previously reported. In stringent strains the normal, preshift rate was reestablished within 2 to 3 min, whereas in relaxed strains the chain growth rate remained low for about 20 min before slowly returning to the normal value, which was reestablished some 50 to 60 min after the shift. Throughout this transition, the stability of messenger ribonucleic acid (mRNA) remained unchanged in both strains. We interpret these findings as evidence of the more rapid reduction of the mRNA pool in the stringent strain after shift-down: we believe that very soon after the shift, the stringent strain reduces its pool of mRNA and with it the number of ribosomes engaged in protein synthesis. In this manner the number of active ribosomes is adjusted to the availability of energy and carbon. The relaxed strain cannot rapidly reduce its mRNA pool, which thus remains large enough to engage a near-preshift number of ribosomes during a prolonged period; as a consequence its ribosomes must work at a reduced rate. The possibility that ppGpp is involved in the control of mRNA production is discussed. After shift-down, the initial part of beta-galactosidase (the auto-alpha fragment) was produced at a higher rate than complete beta-galactosidase in the relaxed strain, as expected when translation is impeded.
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