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  • Book
    Bobby Desai, Alpa Desai, editors.
    Summary: This book is written for physicians who work within an emergency department or urgent care setting to provide them with a treatment plan for those patients who are deemed not to have an emergency medical situation and can be safely treated as an outpatient. Emergency physicians (EPs) see a wide variety of patients and ostensibly for emergency reasons. However, many patients present to the emergency department for primary care-related reasons due to multiple factors or are diagnosed with potentially chronic problems that require a primary care intervention. Examples include a new diagnosis of hypertension (without hypertensive emergency) or diabetes. Thus, it is prudent for the EP to learn about basic primary care management of these conditions. Unfortunately, the training of EPs does not include these conditions, and they are left to guess appropriate treatment or to start a new medication that may not be appropriate. This book aims to fill this gap by educating the EP on basic primary care interventions for specific conditions.

    Contents:
    Headache
    Eye Issues (Stye, etc) + The Red Eye
    Ear Pain + Cerumen Impaction
    Oral Issues (Sore throat, etc) + Dental Pain
    Cough, Cold & Congestion
    Allergies (Allergic rhinitis, etc) Sinonasal Disease
    Neck Pain Dysphagia + Odynophagia
    Noncardiac chest pain, including chest wall pain
    Hypertension
    GERD/Heartburn
    Dyspnea
    Hemoptysis
    Abdominal pain
    Irritable bowel syndrome
    Bloating
    Constipation
    Diarrhea
    Hemorrhoids
    Vaginal problems
    Dysmenorrhea
    Diabetes Mellitus
    Back pain including Sciatica
    Skin problems (including scabies)
    Insomnia
    Anxiety
    Depression.
    Digital Access Springer 2017
  • Article
    Mackler BF, O'Neill PA, Meistrich M.
    Eur J Immunol. 1977 Feb;7(2):55-61.
    Mononuclear cells (MNC) from normal humans consistently failed to give nonspecific cytotoxic responses. However, after removal of T cells by sheep erythrocyte (E) rosetting, the remaining non-RFC (rosette-forming cells) now gave significant nonspecific cytotoxic responses against both autologous and allogeneic target cells. Reconstitution experiments with T cell subpopulations failed to suppress these nonspecific non-E-RFC-mediated cytotoxic responses. There was also no evidence to indicate the involvement of antibody in this nonspecific cytotoxicity. The cytotoxic cells were characterized as non-E-rosetting, non-phagocytic, and glass adherent lymphocytes; no evidence of monocyte-macrophage participation was found. The inductive trigger of non-E-RFC-mediated cytotoxicity was found to be soluble factors released by T cells during E-rosette formation at 4 degrees C. Incubation of MNC with horse, marmoset and human erythrocytes under identical conditions failed to trigger cytotoxicity. The incubation of quiescent MNC with E-rosetting supernatants (ERS) induced nonspecific cytotoxic responses equivalent to those mediated by separated non-E-RFC. ERS-activated MNC destroyed both autologous and allogeneic target cells. The ERS supernatants themselves were not cytolytic. These findings suggested that cell separation procedures, and possibly in vivo events, which activate T cells may also induce non-T cell-mediated nonspecific cytotoxicity.
    Digital Access Access Options