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  • Book
    Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal, editors.
    Summary: "Second comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases. Food and drug administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. Thus dietary agents which can modulate inflammatory pathways in humans, are likely to exhibit enormous potential. Leading experts describe the latest results of anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases"--Publisher's description.

    Contents:
    Cinnamon and chronic diseases / Mitra Hariri, Reza Ghiasvand
    Silymarin and its role in chronic diseases / Neha, Amteshwar S. Jaggi, Nirmal Singh
    Eugenol and its role in chronic diseases / S. Fujisawa, Y. Murakami
    Catechins and its role in chronic diseases / Yohei Shirakami, Hiroyasu Sakai, Takahiro Kochi, Mitsuru Seishima, Masahito Shimizu
    Capsaicin and its role in chronic diseases / E. S. Fernandes, A. R. A. Cerqueira, A. G. Soares, Soraia K. P. Costa
    Diallyl sulfide and its role in chronic diseases prevention / Shankar Suman, Yogeshwer Shukla
    Lupeol and its role in chronic diseases / Fan-Shiu Tsai, Li-Wei Lin, Chi-Rei Wu
    Gingerol and its role in chronic diseases / Yasmin Anum Mohd Yusof
    Potential use of flavopiridol in treatment of chronic diseases / Thejal Srikumar, Jaya Padmanabhan
    Plumbagin and its role in chronic diseases / Pharkphoom Panichayupakaranant, Md Iftekhar Ahmad
    Anethole and its role in chronic diseases / Ana Clara Aprotosoaie, Irina-Iuliana Costache, Anca Miron
    The role of indirubins in inflammation and associated tumorigenesis / Xinlai Cheng, Karl-Heinz Merz
    CDDO and its role in chronic diseases / Bryan J. Mathis, Taixing Cui
    Evodiamine and its role in chronic diseases / Qunyou Tan, Jingqing Zhang
    Guggulsterone and its role in chronic diseases / Takanori Yamada, Ken Sugimoto
    Deguelin and its role in chronic diseases / Jonathan Boyd, Alice Han
    Quercetin and its role in chronic diseases / Ganiyu Oboh, Ayokunle O. Ademosun, Opeyemi B. Ogunsuyi
    Eucalyptol and its role in chronic diseases / Geun Hee Seol, Ka Young Kim
    Auraptene and its role in chronic diseases / Giuseppe Derosa, Pamela Maffioli, Amirhossein Sahebkar.
    Digital Access Springer 2016
  • Article
    Ali IU, Mautner V, Lanza R, Hynes RO.
    Cell. 1977 May;11(1):115-26.
    Transformed cells lack a large, external, transformation-sensitive (LETS) glycoprotein which is a major surface component of their normal counterparts. Addition of LETS glycoprotein isolated from normal cells to transfomed cells restores certain morphological features and adhesive properties characteristic of normal cells. LETS protein is detected on the cell surface both by iodination using lactoperoxidase and by immunofluorescent staining. The surface distribution pattern detected by immunofluorescence is strikingly similar to that of normal cells. After addition of LETS protein, transformed cells also exhibit well defined actin cables which are not seen in untreated, transformed cells. All these alterations can be blocked by treating LETS protein with specific antisera or by subjecting it to mild trypsinization prior to addition to transformed cells. The effects are rapidly reversible by mild trypsinization, which removes the added LETS protein. The high rate of uptake of 2-deoxyglucose, characteristic of transformed cells, is not affected by LETS protein. These results suggest that LETS protein may have a role in cell attachment and spreading, and affect the organization of cytoskeleton.
    Digital Access Access Options