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  • Book
    Mario D. Cordero, Benoit Viollet, editors.
    Contents:
    Part I: AMPK in health
    Structure and Regulation of AMPK
    AMPK Regulation of Carbohydrate Metabolism
    AMPK Regulation of Lipid Metabolism
    AMPK Regulation of Protein Metabolism
    AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics
    AMPK Regulation of immunology
    AMPK and Stem Cells
    Part II: AMPK in the diseases
    AMPK in metabolic diseases
    AMPK in neurodegenerative diseases
    AMPK in cardiovascular diseases
    AMPK in cancer
    AMPK in aging
    AMPK in musculoskeletal diseases and pain
    AMPK in pathogens
    Part III: Pharmacology of AMPK
    Metformin, new drugs and AMPK
    Small molecules and AMPK
    Nutraceutical compounds and AMPK
    Part IV: Methods of study in AMPK
    Animal models
    In vitro study methods.
    Digital Access Springer 2016
  • Article
    Cooke ED, Dawson MH, Ibbotson RM, Bowcock SA, Ainsworth ME, Pilcher MF.
    J Bone Joint Surg Am. 1977 Jun;59(4):496-500.
    In a double-blind, randomized trial of orally administered hydroxychloroquine sulphate in the prevention of venous thromboembolism after elective surgery on the hip, the drug or a placebo was given to fifty consecutive patients. Therapy was commenced on the day before the operation and continued for fourteen days. The diagnosis of deep venous thrombosis was made by daily thermographic scanning of the legs and confirmed by phlebography. The diagnosis of pulmonary embolism was made by perfusion lung scanning. No significant difference in the incidence of thromboembolism was found between treated and control groups. The results provide evidence that substances which reduce the incidence of thromboembolism in general surgery may not be effective in operations on the hip.
    Digital Access Access Options