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  • Book
    Electron Kebebew, editor.
    Summary: This book is designed to present a comprehensive and state-of the-art approach to the management of adrenal neoplasms that provides a resource to the broad group of providers that will encounter such a patient. Sections address issues that are faced by providers who encounter a patient with an adrenal neoplasm. These areas include an overview of the genetic basis and familial cancer syndrome-associated with adrenal neoplasms, pathobiology, advanced and tumor specific imaging approaches and technologies, biochemical analysis, standard medical and surgical therapies, and emerging technology and treatment approaches to benign and malignant adrenal neoplasms. Written by experts in the field, each of these sections address level of clinical evidence and provide recommendations and treatment algorithms. Extensive illustrations make this an interactive text. Management of Adrenal Masses in Children and Adults will serve as a very useful resource for all providers dealing with, and interested in this common but challenging tumor. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.

    Contents:
    Epidemiology of Adrenal Neoplasms
    The Pathology of Adrenal Masses
    Genetics of Benign Adrenocortical Tumors
    Genetics of Adrenocortical Cancers
    Genetics of Pheochromocytoma and Paraganglioma
    Imaging Modalities for Adrenocortical Tumors
    Imaging Modalities for Pheochromocytoma and Paraganglioma
    Primary Hyperaldosteronism
    Cushing Syndrome: Presentation, Diagnosis, and Treatment, Including Subclinical Cushing Syndrome
    Management of Pheochromocytoma and Paraganglioma
    Congenital Adrenal Hyperplasia
    Adrenocortical Carcinoma
    Operative Techniques for Adrenal Neoplasms
    Therapies for Locally Advanced and Metastatic Adrenocortical Carcinoma
    .
    Digital Access Springer 2017
  • Article
    Hermon-Taylor J, Perrin J, Grant DA, Appleyard A, Bubel M, Magee AI.
    Gut. 1977 Apr;18(4):259-65.
    The distribution of enterokinase in human intestine was studied in operative mucosal biopsies using specific antiserum to human enterokinase, previously purified to apparent homogeneity by affinity chromatography and immunoabsorption. Fluorescence was observed in the brush-border and glycocalyx of the duodenum and proximal 15 cm of jejunum distal to the D/J flexure. Distal jejunum and ileum as well as stomach and colon were consistently negative. Brunner's glands and goblet cells were never stained by specific antibody. Preliminary evidence was obtained that the human enterokinase molecule contains a specific antigenic determinant in its polypeptide component and a second determinant in the oligosaccharide moiety which cross-reacts with blood group A. Preliminary evidence was also obtained that mucosal synthesis of enterokinase may be impaired in jaundice due to carcinoma of the pancreas and induced in the small intestine distal to the normal limit of synthesis after pancreatico-duodenectomy.
    Digital Access Access Options