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  • Book
    Massimo Loda, Lorelei A. Mucci, Megan L. MIttelstadt, Mieke Van Hemelrijck, Maura Bríd Cotter, editors.
    Contents:
    Basic Principles of Patho-Epidemiology
    The Intersection of Epidemiology and Pathology
    Introduction to Histology
    Introduction to Pathology
    Basic Techniques in Molecular Pathology
    Introduction to Cancer Epidemiology
    Cancer Screening
    Molecular and Genetic Epidemiology of Cancer
    Bioinformatic Analysis of Epidemiological and Pathological Data
    Cancer Types
    Epidemiology of Prostate Cancer
    Pathology and Molecular Pathology of Prostate Cancer
    Epidemiology of Breast Cancer
    Pathology and Molecular Pathology of Breast Cancer
    Epidemiology of Ovarian and Endometrial Cancer
    Pathology and Molecular Pathology of Uterine and Ovarian Cancers
    Brain Tumors
    Epidemiology
    Pathology and Molecular Pathology of Brain Cancer
    Epidemiology of Renal Cell Carcinoma
    Pathology and Molecular Pathology of Renal Cancer
    Epidemiology of Lung Cancer
    Pathology and Molecular Pathology of Lung Cancer
    Epidemiology of Colorectal Cancer
    Pathology and Molecular Pathology of Colorectal Cancer
    Epidemiology of Hepatocellular Carcinoma
    The Pathology and Molecular Pathology of Hepatocellular Carcinoma
    Epidemiology of Pancreatic Cancer
    Pathology and Molecular Pathology of Pancreatic Cancer
    Epidemiology of Bladder Cancer
    Bladder Cancer
    Epidemiology of Hematologic Malignancies
    Pathology and Molecular Pathology of Hematologic Malignancies
    Epidemiology of Melanoma
    Pathology and Molecular Pathology of Melanoma.
    Digital Access Springer 2017
  • Article
    Fournier C, Lesavre P, Bach JF.
    Transplantation. 1977 Mar;23(3):239-47.
    Cellular receptors for the Fc fragment of IgG have been studied by the erythrocyte antibody (EA) rosette technique using either human red blood cells coated with anti-D IgG alloantibodies or pigeon red blood cells coated with aggregated IgG. Human lymphocytes were shown to form 4 to 35% of anti-D EA rosettes and 15% of E-aggregated IgG rosettes. Anti-D EA rosette values depended closely upon the amount and the source of anti-D antibodies, Ripley's type antisera giving the highest percentage of rosettes. Cell filtration through a nylon-wool column, a procedure known to remove B cells, caused a complete depletion of E-aggregated IgG rosettes and significant but only partial decrease of anti-D EA rosettes. A low but significant percentage of double rosettes were formed when anti-D-coated erythrocytes were mixed with aggregated IgG coated red blood cells or sheep red blood cells. Removal of EA-rosette-forming cells by passage on a Ficoll-Hypaque gradient K cell activity (assessed by lymphocyte-dependent antibody cytotoxicity using anti-HLA antibody-coated target cells) even when forming rosettes at low levels of erythrocyte sensitization with anti-D serum. Conversely, B cell markers (erythrocyte antibody complement rosettes or surface Ig) were only decreased at high levels of erythrocyte sensitization and remained unaffected after depletion of EA-rosette-forming cells formed at low levels of erythrocyte sensitization. These data suggest the existence of several populations of Fc receptor-bearing cells in human peripheral blood which may be differentiated according to the degree of erythrocyte IgG sensitization. Rosettes made with low concentrations of anti-D serum are mainly formed by non-B cells endowed with K cell activity, whereas those formed with high concentration of anti-D serum include B cells, monocytes, and K cells.
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