BookFrederic Shapiro.
Contents:
I. INTRODUCTION
II. MATERIALS AND METHODS
1. Source, distribution, and ages of pudgy and non-affected mice.
2. Whole mount preparations
3. Radiographic studies
4. Histologic studies
5. Computerized three-dimensional reconstructions
6. Previous studies on chick vertebral development and human congenital scoliosis
III. RESULTS
1. Gross appearance
2. Whole mount appearances
3. Radiographic studies
4. Histology studies: vertebrae, ribs, intervertebral discs and ganglia
5. Computerized three-dimensional reconstructions
6. Chick embryo vertebral development
7. Radiology and histopathology of human congenital scoliosis spine
IV. DISCUSSION
ion
3. The pudgy mouse
4. Genetic influences on axial development; mutations identified in mouse models with vertebral deformation
5. Congenital scoliosis (human); its similarity with pudgy mouse vertebral abnormalities
6. Pathogenesis of pudgy and human congenital scoliosis based on histopathologic studies.-V. CONCLUSIONS
1. Implications of pudgy vertebral abnormalities for biologic research
2. Implications of pudgy vertebral abnormalities for clinical patient treatment. .