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- BookDr. Jodie Copley, Dr. Kathy Kuipers.Contents:
Seeing the bigger picture : using clients' experiences to shape clinical practice
What happens to the upper limb after brain injury?
The hypertonicity intervention planning model for upper limb neurorehabilitation
Making sense of the clinical picture : assessment and goal setting
Case studies
Movement and strength training
Splinting
Casting
Botulinum neurotoxin
Surgery
Case studies revisited.Digital Access Wiley 2014 - ArticleSnider SR, Snider RS.J Neural Transm. 1977;40(2):115-28.Projections from the midline cerebellar nuclei to norepinephrine (NE) and dopamine (DA) cell groups in the brain stem have been demonstrated histologically. To determine if these connections are significant biochemically, unilateral electrolytic lesions were placed in either vermis or paravermis and levels of DA, NE and gamma-aminobutyric acid (GABA) were measured in each half of the forebrain at 1 1/2, 3 or 6 weeks. In the cerebral hemisphere ipsilateral to a vermis lesion, there was a decrease in NE levels at 3 and 6 weeks. Relative to the opposite side DA was also reduced at 3 and 6 weeks. Paravermal lesions caused a contralateral reduction in DA at 3 weeks but no change in NE. GABA was only slightly altered. These results suggest that the cerebellum can modify levels and turnover of catecholamines in the brain, possibly via direct anatomic connections as well as by functional interaction with catecholaminergic pathways.