Live Chat
Today's Hours: 8:00am - 8:00pm
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Book
    by Brené Brown.
    Summary: In this work, the author, a leading expert on shame, authenticity, and belonging, shares ten guideposts on the power of wholehearted living, a way of engaging with the world from a place of worthiness.

    Contents:
    Wholehearted living
    Courage, compassion, and connection: the gifts of imperfection
    Exploring the power of love, belonging, and being enough
    The things that get in the way
    Cultivating authenticity: letting go of what people think
    Cultivating self-compassion: letting go of perfectionism
    Cultivating a resilient spirit: letting go of numbing and powerlessness
    Cultivating gratitude and joy: letting go of scarcity and fear of the dark
    Cultivating intuition and trusting faith: letting go of the need for certainty
    Cultivating creativity: letting go of comparison
    Cultivating play and rest: letting go of exhaustion as a status symbol and productivity as self-worth
    Cultivating calm and stillness: letting go of anxiety as a lifestyle
    Cultivating meaningful work: letting go of self-doubt and supposed to
    Cultivating laughter, song, and dance: letting go of being cool and always in control.
    Digital Access ProQuest Ebook Central ©2010
    Limited to 1 simultaneous user
  • Article
    Fozzard HA.
    Annu Rev Physiol. 1977;39:201-20.
    The study of E-C coupling in heart muscle has been facilitated by the recent availability of reasonably reliable voltage clamp techniques and a method of "skinning" cardiac cells. We have also had the introduction of several new ideas, including a Na:Ca exchange pump, metabolically controlled Ca storage capacity of the SR, and length dependence of Ca release. Consideration of the mechanism of E-C coupling in striated muscle as a general model has enabled transfer of insights gained studying fast skeletal muscle to heart muscle. On the other hand, many of the complexities of regulation of heart muscle contraction are manifested in fast skeletal muscle, as investigators explore the details of E-C coupling. On the whole, it is interesting to be an investigator in this field, as the E-C coupling mechanisms under investigation are being located in many nonmuscle cells, for such varied functions as control of cell shape during growth and excitation-secretion coupling. The last few years have seen the establishment of the existence and importance of a channel in the membrane that admits Ca as a function of electric field. We remain uncertain, however, of the details of relation of this current to the size of contraction. We have begun to explore the characteristics and role of the Na:Ca exchange mechanism in regulating the magnitude of intracellular Ca stores. Most investigators feel that this finally represents the necessary link in understanding digitalis action. A powerful but technically demanding tool is available in the "skinned" cardiac cell, permitting direct studies of Ca release from the SR in more-or-less intact cells. One dramatic finding with that technique is the demonstration of length-dependence of Ca release. On the horizon are methods of monitoring any possible transient potentials across subcellular organelle membranes and directly determining transient changes in free Ca in the sarcoplasm. This reviewer cannot help but feel that the next three or four years will be exciting ones in this field, and that the next review of E-C coupling will make interesting reading.
    Digital Access Access Options