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- BookAshwin N. Ananthakrishnan, editor.Summary: This book is a state-of-the art review for clinicians and dieticians with an interest in nutrition and inflammatory bowel diseases (Crohn's disease, ulcerative colitis). The volume covers new data about dietary risk factors for Crohn's disease and ulcerative colitis, examines the association between diet and microbiome, describes the various diets in the management of these diseases, and discusses macro- and micronutrient deficiency that occurs in such patients. The book also examines the management of patients on total parenteral nutrition, and management of the short gut syndrome with TPN and novel pharmacologic therapies. Written by experts in their fields, Nutritional Management of Inflammatory Bowel Diseases: A Comprehensive Guide is a valuable and uniquely specialized resource for gastroenterologists, nutritionists, primary care physicians, and other health care providers and researchers dealing with the management of these complex illnesses. .
Contents:
Diet and Microbiome in Inflammatory Bowel Diseases
Dietary Risk Factors for the Onset and Relapse of Inflammatory Bowel Disease
Vitamin D and Inflammatory Bowel Diseases
Diagnosis and Management of Iron Deficiency in Inflammatory Bowel Disease
Other Micronutrient Deficiencies in Inflammatory Bowel Disease: From A to Zinc
Enteral Nutrition in the Treatment of Inflammatory Bowel Disease
Elimination Diets for Inflammatory Bowel Disease
Prebiotics and Probiotics in Inflammatory Bowel Disease
Total Parenteral Nutrition and Inflammatory Bowel Disease: Indications, Long term Outcomes and Complications
Short Bowel Syndrome: Physiologic Considerations and Nutritional Management
Short Bowel Syndrome: Pharmacotherapy
Small Bowel Transplantation. . - ArticleSiwers B, Borg S, d'Elia G, Lundin G, Forshell GP, Raotma H, Román G.Acta Psychiatr Scand. 1977 Jan;55(1):21-31.A multicentre comparative clinical evaluation of lofepramine, an imipramine analogue, and imipramine has been made with double-blind technique and fixed dosage (lofepramine 70 mg t.i.d., imipramine 50 mg t.i.d.). Plasma was drawn after 3 weeks for determination of noradrenaline-uptake inhibitory capacity of the parent compound and/or its active metabolites. Plasma concentrations of lofepramine and desmethylimipramine (DMI) were determined in the same samples. The concentrations of lofepramine in the whole material were low (5-27 ng/ml) except for one patient who had a level of 53 ng/ml. In both groups of patients there was an almost 40-fold range in the plasma levels of DMI or apparent DMI. The patients were rated for severity of depression before treatment, then once weekly for 3 weeks and finally during the fifth week. For further information concerning the psychiatric aspects, see d'Elia et al. in this issue (1977). A significant correlation was found between the concentrations of DMI and the noradrenaline-uptake inhibitory capacity in the plasma samples. No correlations were found between uptake inhibitory capacity of plasma samples and the amelioration scores.