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  • Book
    Douglas W Arthur, Frank A. Vicini, David E. Wazer, Atif J. Khan, editors.
    Contents:
    PART I: Accelerated Breast Irradiation: History, Rationale, and Controversies
    Pathologic Anatomy of Early-Stage Breast Cancer: Defining the Target
    The Radiobiology of Accelerated Breast Irradiation
    Quality Assurance and Radiation Safety/Medical Events
    Surgical Considerations in Partial Breast Irradiation
    Impact of Oncoplastic Surgery on adjuvant XRT
    Comparison of true cost between modalities in a changing health care system
    PART II: Hypofractionated WBI: Patient Selection
    Physics of HWBI
    Treatment History
    PART III: Accelerated Partial Breast Irradiation: Patient Selection
    Physics of Accelerated Partial Breast Irradiation
    Interstitial brachytherapy
    Intracavitary brachytherapy
    3D-Conformal external beam radiotherapy
    PART IV: Intra-operative Radiation Therapy: Patient Selection
    Physics of IORT
    50 kV Photons: Targeted Intraoperative Radiotherapy (TARGIT)
    Intraoperative Technique with Electrons
    PART V: Emerging treatment approaches: Extreme hypofractionation (brachytherapy, Gammapod, UK FAST WBI)
    APBI for breast augmentations
    Accuboost
    APBI for in-breast recurrence following WBI
    Preoperative partial breast
    Locoregional Hypofractionation
    PART VI: Hypofractionation for metastatic disease: Stereotactic treatment for Oligometastatic disease
    Hypofractionaton for palliation.
    Digital Access Springer 2016
  • Article
    Kamegashira M, Goodale RL, Borner JW, Dhingra U, Wangensteen OH.
    Arch Surg. 1977 Feb;112(2):193-7.
    This controlled study shows that the rabbit is more vulnerable to erosive gastritis after stress of operation, weight loss, and hypersecretion or acute ischemia than is the cat. Rabbit gastric juice also produces more erosions in the Shay rat preparation after four hours than does cat gastric juice (P less than .05). In vitro, rabbit pepsin has 1.5 times greater specific activity and possesses other kinetic differences. The deleterious effect of these qualitative differences on gastric mucosa may also be augmented by quantitative differences. Hypersecretion of pepsin has been reported once the mucosa is damaged. We conclude that demonstration of species-related differences in pepsin activity helps to explain an apparent discrepancy noted by others--namely, why the rabbit is so much more susceptible to stress-produced erosions than the cat or other experimental animals.
    Digital Access Access Options