Search

Search Results

• Book

  Economic evaluation in genomic medicine

  Vasilios Fragoulakis, Christina Mitropoulou, Marc S. Williams, George P. Patrinos.

  Contents:
  Economic evaluation in health care: evidence-based medicine and evidence-based health economics
  Genomic medicine today: an introduction for health economists
  Economic evaluation and genomic medicine: what can they learn from each other?
  Introduction to the technical issues of economic evaluation
  Advanced methodological aspects in the economic evaluation
  Economic evaluation in the genomic era: some examples from the field
  Special requirements for economic evaluation and health technology assessment in genomic medicine
  A new methodological approach for cost-effectiveness analysis in genomic medicine
  Conclusions and future perspectives.

  Digital Access ScienceDirect 2015
  Get Shareable Link

  View Details
• Article

  Introduction of bacteriophage Mu into Pseudomonas solanacearum and Rhizobium meliloti using the R factor RP4.

  Boucher C, Bergeron B, De Bertalmio MB, Dénarié J.

  J Gen Microbiol. 1977 Jan;98(1):253-63.

  Phage Mu-1 and a thermoinducible derivative, Mu-1 cts 62 were inserted into the broad host range R factor RP4. These hybrid plasmids were transferred by conjugation to a phytopathogenic bacterium Pseudomonas solanacearum GMI 1000 and a legume-root nodule bacterium Rhizobium meliloti 2011. The Mu genome is transcribed and tranlated in these new hosts: P. solanacearum (RP4:Mu cts) cultures have a spontaneous production of about 5 X 10(5) plaque-forming units ml-1 which is similar to the frequency of spontaneous Mu production in E. coli; the Mu production of R. meliloti is lower (about 10(2) plaque-forming units ml-1).

  Digital Access Access Options
  Get Shareable Link

  PubMed