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  Xenotransplantation-- methods and protocols

  edited by Cristina Costa, Rafael Máñez.

  Contents:
  Xenotransplantation : an overview of the field / Veronica Tisato and Emanuele Cozzi
  Cloning and expression analyses of pig genes / Mireia Uribe-Herranz and Cristina Costa
  Basic analyses of proteins of interest for xenotransplantation / Mireia Uribe-Herranz and Cristina Costa
  Studies on carbohydrate xenoantigens / Dale Christiansen [and others]
  Xenoantibodies and complement activity determinations in pig-to-primate xenotransplantation / Nieves Domenech
  Studies on coagulation incompatibilities for xenotransplantation / Cristiana Bulato, Claudia Radu, and Paolo Simioni
  Cellular studies for in vitro modeling of xenogeneic immune responses / Roberta Sommaggio, Magdiel Perez-Cruz, and Cristina Costa
  Production of transgenic and knockout pigs by somatic cell nuclear transfer / Angelica M. Giraldo, Suyapa Ball, and Kenneth R. Bondioli
  Small animal models of xenotransplantation / Hao Wang
  Heart xenotransplantation in primate models / Johannes Postrach [and others]
  Xenogeneic lung transplantation models / Lars Burdorf, Agnes M. Azimzadeh, and Richard N. Pierson, III
  Thymic transplantation in pig-to-nonhuman primates for the induction of tolerance across xenogeneic barriers / Kazuhiko Yamada and Joseph Scalea
  Isolation of porcine pancreatic islets for xenotransplantation / Karin Ulrichs [and others]
  Pig neural cells derived from foetal mesencephalon as cell source for intracerebral xenotransplantation / Xavier Leveque [and others]
  Hepatocyte xenotransplantation / Katia R.F. Lima-Quaresma [and others]
  In vitro repair model of focal articular cartilage defects in humans / Diaz Prado SM, Fuentes-Boquete IM, and Blanco FJ
  Potential zoonotic infection of porcine endogenous retrovirus in xenotransplantation / Giada Mattiuzzo, Yasuhiro Takeuchi, and Linda Scobie
  Ethical and regulatory issues for clinical trials in xenotransplantation / Jorge Guerra Gonzalez
  Some ethical, social, and legal considerations of xenotransplantation / Maria Jorqui Azofra and Carlos Maria Romeo Casabona.

  Digital Access Springer 2012
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• Article

  Regional assignment of seven genes on chromosome 1 of man by use of man-Chinese hamster somatic cell hybrids. II. Results obtained after induction of breaks in chromosome 1 by X-irradiation.

  Burgerhout WG, Smit SL, Jongsma AP.

  Cytogenet Cell Genet. 1977;18(5):267-83.

  The position of genes coding for PGD, PPH1, UGPP, GuK1, PGM1, Pep-C, and FH on human chromosome 1 was investigated by analysis of karyotype and enzyme phenotypes in man-Chinese hamster somatic cell hybrids carrying aberrations involving chromosome 1. Suitable hybrid cell lines were obtained by X-irradiation of hybrid cells carrying an intact chromosome 1 and by fusion of human cells from a clonal population carrying a translocation involving chromosome 1 with Chinese hamster cells. The latter human cell population had been isolated following X-irradiation of primary Lesch-Nyhan fibroblasts. In addition, products of de novo chromosome breakage in the investigated hybrid lines were utilized. By integrating the results of these analyses with earlier findings in our laboratory, the following positions of genes are deduced: PGD and PPH1 in 1p36 leads to 1p34; PGM1 in 1p32; UGPP in 1q21 leads to 1q23; GuK1 in 1q31 leads to 1q42; Pep-C in 1q42; and FH in 1qter leads to 1q42.

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  PubMed