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  • Book
    editor M. Dawn Teare.
    Contents:
    Molecular genetics and genetic variation / Mohammed-Elfatih Twfieg and M. Dawn Teare
    Terminology, concepts, and models in genetic epidemiology / M. Dawn Teare and Mauro F. Santibàñez Koref
    An introduction to epidemiology / Cother Hajat
    Genetic distance and markers used in linkage mapping / Kristina Allen-Brady and Nicola J. Camp
    Approaches to genetic linkage analysis / M. Dawn Teare
    Fine-scale structure of the genome and markers used in association mapping / Karen Curtin and Nicola J. Camp
    Genome-wide association studies / Mark M. Iles
    Candidate gene association studies / M. Dawn Teare
    Family-based association studies / Frank Dudbridge
    Genome variation : a review of web resources / Andrew Collins and William J. Tapper
    Advanced methods in twin studies / Jaakko Kaprio and Karri Silventoinen
    Mendelian randomisation : a tool for assessing causality in observational epidemiology / Nuala A. Sheehan, Sha Meng, and Vanessa Didelez
    Copy number variation / Louise V. Wain and Martin D. Tobin
    Epigenetic variation / Kevin Walters
    Modeling the effect of susceptibility factors (HLA and PTPN22) in rheumatoid arthritis / Hervé Perdry and Françoise Clerget-Darpoux
    Coronary artery disease : an example case study / Jennifer H. Barrett
    The genetic epidemiology of obesity : a case study / Laura M. Johnson.
    Digital Access Springer 2011
  • Article
    Belal A, Linthicum FH, House WF.
    Am J Otol. 1979 Oct;1(2):72-9.
    A patient with Meniere's disease underwent a middle fossa superior and inferior vestibular nerve section with excision of Scarpa's ganglia. Studies of this patient's temporal bone, conducted two and one-half years post-operatively, showed normal cochlear and facial nerves. The internal auditory canal showed fibrosis and new periosteal bone formation. There was complete denervation of the vestibular labyrinth except for the posterior semicircular canal crista. Fibrous and osteoid tissue filled the superior and lateral semicircular canals. In this case, these severe degenerative changes, presumably associated with biochemical changes in the vestibular labyrinth, altered the natural course of Meniere's disease. Vertigo was completely relieved, tinnitus improved, and hearing thresholds stabilized during the course of post-operative follow-up.
    Digital Access Access Options