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- Bookedited by Richard Milner.Contents:
Cerebral Angiogenesis During Development: Who is Conducting the Orchestra?
Cerebral Angiogenesis: A Realistic Therapy for Ischemic Disease?
Vascular Normalization in Cerebral Angiogenesis: Friend or Foe?
Pericytes and Adaptive Angioplasticity: The Role of Tumor Necrosis Factor Weak Inducer of Apoptosis (TWEAK)
Analysis of Angiogenesis in the Developing Mouse Central Nervous System
Hypoxia-Induced Angiogenesis and Capillary Density Determination
The Middle Cerebral Artery Occlusion Model of Transient Focal Cerebral Ischemia
A Mouse Model of Chronic Cerebral Hypoperfusion Characterizing Features of Vascular Cognitive Impairment
A Mouse Model of Permanent Focal Ischemia: Distal Middle Cerebral Artery Occlusion
A Method of Inducing Global Cerebral Ischemia
Induction of Cerebral Arteriogenesis in Mice
Vessel Painting Technique for Visualizing the Cerebral Vascular Architecture of the Mouse
Examining Cerebral Angiogenesis in Response to Physical Exercise
Histological Assessment of Angiogenesis in the Hypoxic Central Nervous System
Examining Vascular Remodeling in the Hypoxic Central Nervous System
Analysis of Cerebral Angiogenesis in Human Glioblastomas
Quantitative Cerebral Blood Flow Measurements Using MRI
Fluorescent Angiogenesis Models Using Gelfoam? Implanted in Transgenic Mice Expressing Fluorescent Proteins
Laser Speckle Contrast Imaging to Measure Changes in Cerebral Blood Flow
Laser Doppler Flowmetry to Measure Changes in Cerebral Blood Flow
Defining the Role Of HIF and Its Downstream Mediators in Hypoxic-Induced Cerebral Angiogenesis
Inducible Gene Deletion in Glial Cells to Study Angiogenesis in the Central Nervous System
Bone Marrow Chimera Experiments to Determine the Contribution of Hematopoietic Stem Cells to Cerebral Angiogenesis
Novel Methods for Accurate Identification, Isolation, and Genomic Analysis of Symptomatic Micro-Environments in Atherosclerotic Arteries
Induction of Brain Arteriovenous Malformation in the Adult Mouse
Stimulation of Cerebral Angiogenesis by Gene Delivery
Investigating the Role of Perlecan Domain V in Post-Ischemic Cerebral Angiogenesis
Isolation and Culture of Primary Mouse Brain Endothelial Cells
Purification of Endothelial Cells from the Rat Brain
Generation of Primary Cultures of Bovine Brain Endothelial Cells and Setup of Co-Cultures with Rat Astrocytes
Isolation and Culture of Primary Pericytes from Mouse Brain
Assays to Examine Endothelial Cell Migration, Tube Formation, and Gene Expression Profiles
A Neurovascular Blood-Brain Barrier In Vitro Model
In Vitro Models of the Blood-Brain Barrier. - ArticleVizethum W, Goerz G.Chem Biol Interact. 1979 Dec;28(2-3):291-9.The application of hexachlorobenzene (HCB), pentachlorophenol (PCP) and 2,4,5-trichlorophenol (TCP) to female rats led to an induction of both the microsomal and the nuclear cytochrome P-450 system in the liver. The increase of th mixed-function hydroxylase activities examined (7-ethoxycoumarin deethylase, 7-ethoxyresorufin deethylase, NADPH-dependent cytochrome c reductase, aminopyrine demethylase, benzpyrene hydroxylase) did not correlate strictly with the cytochrome P-450 content. Depending on the inducers and the substrates used, the content and the activity of the cytochrome P-450 were essentially smaller in the nuclei than in the microsomes. It was striking that in the nuclei those activities (benzpyrene hydroxylase, 7-ethoxyresorufin deethylase, 7-ethoxycoumarin deethylase) were preferably induced which can be attributed to the methyl-cholanthrene-induced form of the cytochrome P-450 (cytochrome P-448). These results suggest, also in the light of findings of other authors, the induction of different species of cytochrome P-450 in the nuclei and microsomes.