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  • Book
    edited by Michael Steinitz.
    Contents:
    Human monoclonal antibodies : the residual challenge of antibody immunogenicity / Herman Waldmann
    Technical and ethical limitations in making human monoclonal antibodies (an overview) / Mark C. Glassy and Rishab Gupta
    Therapeutic human monoclonal antibodies in inflammatory diseases / Sotirios Kotsovilis and Evangelos Andreakos
    Therapeutic human monoclonal antibodies against cancer / Jamie Jarboe, Anumeha Gupta, and Wasif Saif
    Polyclonal and monoclonal antibodies in clinic / Bharath Wootla, Aleksandar Denic, and Moses Rodriguez
    Production of human monoclonal Antibodies by the Epstein-Barr virus method / Michael Steinitz
    Humanization and simultaneous optimization of monoclonal antibody / T. Kuramochi, T. Igawa, H. Tsunoda, and K. Hattori
    Chimeric Antibodies / Kohei Kurosawa, Waka Lin, and Kunihiro Ohta
    Recombinant genetic libraries and human monoclonal antibodies / Jarrett J. Adams, Bryce Nelson, and Sachdev S. Sidhu
    Production of stabilized scFv antibody fragments in the E. coli bacterial cytoplasm / Lilach Vaks and Itai Benhar
    Construction and production of an IgG-like tetravalent bispecific antibody, IgG-single-chain Fv fusion / Dan Lu and Zhenping Zhu
    Construction of human antibody gene libraries and selection of antibodies by phage display / André Frenzel [and others]
    Antigen-specific human monoclonal antibodies from transgenic mice / Susana Magadán Mompó and África González-Fernández
    Phage display technology for human monoclonal antibodies / Cecilia Deantonio [and others]
    Antigen-specific in vitro immunization : a source for human monoclonal antibodies / Kosuke Tomimatsu and Sanetaka Shirahata
    Methods for radiolabelling of monoclonal antibodies / Vladimir Tolmachev, Anna Orlova, and Karl Andersson
    Purification of human monoclonal antibodies and their fragments / Thomas Müller-Späth and Massimo Morbidelli
    Idiotype-specific intravenous immunoglobulin (IVIG) for therapy of autoimmune diseases / Miri Blank, Tomer Bashi, and Yehuda Shoenfeld.
    Digital Access Springer 2014
  • Article
    Walker DI, Eisen V.
    Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Oct;36(4):399-407.
    Whole body irradiation of mice with 200-1000 R of unfiltered X-radiation (230 kV, 15 mA, 140 R/min) produced extensive falls of 15-hydroxy prostaglandin dehydrogenase (PGDH) activity in the spleen within 4 hours. A transient recovery between 4 and 72 hours was followed by a second reduction in PGDH levels which was still evident 7 days after exposure. In the jejunum and kidney, the falls were smaller. High doses (1000 R) increased PGDH activity in the lung. Effects of radiation on the other cellular enzymes, including other dehydrogenases in the cytosol, were less pronounced, and in some cases the opposite of the effects on PGDH. The loss of PGDH may contribute to the increase in prostaglandin concentrations in the spleen and jejumun, and thereby to some features in radiation sickness.
    Digital Access Access Options