ArticleZielinski A.
Acta Otorhinolaryngol Belg. 1979;33(4):516-21.
The immunological reaction of immediate as well as delayed type is produced in patients with pollinosis by the contact with pollen allergens. The immunological disturbances partially connected with function of T and B lymphocytes can be treated as the basal mechanism of pollinosis. The presence of surface immunoglobulins (SIg) from classes IgA, IgG and IgM on the B lymphocytes in circulating blood from the patients with pollinosis in various stages of the disease were studied. The method of direct immunofluorescence was used. The decrease of B lymphocytes with SIg of IgG was found. On the basis of presence SIg (IgA, IgG, IgM) on lymphocytes the four periods of various immunological reaction in pollinosis were differentiated: I - primary immunological response, II - secondary immunological response, III - immunological exhaust, IV - immunological stabilization.