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- BookJadelson P. Andrade, Fausto J. Pinto, Donna K. Arnett, editors.Contents:
Global burden of non-transmissible chronic diseases.- A global perspective about cardiovascular diseases.- Value of primary prevention for cardiovascular diseases.- How to estimate cardiovascular risk.- Tobacco and alcohol control
preventable risk factors.- Physical inactivity: preventable risk factor for cardiovascular diseases.- Diet and cardiovascular health: global challenges and opportunities.- Raised blood cholesterol: preventable risk factor for cardiovascular diseases.- Hypertension: primary health care approach.- Diabetes: a primary health care approach
Risk factors in childhood and youth.- Other determinants in cardiovascular diseases: social impact, globalization and urbanization.- Genetics of cardiovascular diseases.- Cardiovascular diseases in women: an update
Rheumatic heart disease: a neglected condition.- Chagas disease.- Prevention and control of cardiovascular: policies, strategies and prevention.- Prevention and control of cardiovascular in low income countries.- Prevention and Control of cardiovascular: What Works?.- Prevention and control of cardiovascular: integrated and complementary strategies.- Post-traumatic stress disorders and cardiovascular diseases.- Individual interventions for prevention and control of cardiovascular diseases.- Social mobilization on prevention and control of cardiovascular diseases.- Frugal Innovation: Solutions for Sustainable Global Cardiovascular Health.- Atrial fibrillation and stroke prevention.- A global alliance for cardiovascular diseases prevention in clinical practice.- Priority areas for cardiovascular research.- Evidence for preventing cardiovascular diseases.Digital Access Springer 2015 - ArticleKamiya-Harada Y, Kawakami M.Microbiol Immunol. 1979;23(12):1199-209.Heterogeneity of antibodies directed against the trinitrophenyl (TNP) determinant in immunized mice was analyzed by investigating the band groups of antibodies formed by thin layer isoelectric focusing of serum. The degree of heterogeneity in C57BL/6 mice was markedly higher than that in CBA mice under the following conditions of immunization: immunization with TNP conjugated with bovine gamma-globulin or ovalbumin, interchange of these carrier proteins at the first and second injections, change of epitope density of the antigens, replacement of the hapten by dinitrophenyl group on the antigen for the secondary stimulation, and change of intervals of these injections from 15 days to five months. The degree of heterogeneity within a strain also varied with these immunizing conditions. Furthermore, the heterogeneity in C57BL/6 mice of any immunization group was greater than that in CBA mice in any group. This was also true when the heterogeneity was examined with the immune sera diluted to the same titer. These results indicate that the number of predominant clones of cells producing anti-TNP antibody after immunization is larger in C57BL/6 than in CBA mice.