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  • Book
    Mohit Kapoor, Nizar N. Mahomed, editors.
    Contents:
    1. Pathogenesis of Osteoarthritis
    2. Hip and Knee Osteoarthritis
    3. Shoulder and Elbow Osteoarthritis
    4. Lumbar Spine Osteoarthritis
    5. Ankle Osteoarthritis
    6. Hand and Wrist Osteoarthritis
    7. Imaging in Osteoarthritis
    8. Osteoarthritis : Joint Conservation Strategies
    9. Osteoarthritis Biomarkers
    10. Drug/Agent Treatments for Osteoarthritis : Present and Future
    11. Safety Profile of Current OA Therapies : Evidence from Clinical Trials
    12. Regenerative Medicine Approaches for Treatment of Osteoarthritis
    13. Precision Medicine for Osteoarthritis.
    Digital Access Springer 2015
  • Article
    Nishimura K, Miyaji M.
    Mycopathologia. 1979 Sep 28;68(3):145-53.
    Cryptococcosis in nude (nu/nu) mice was examined histopathologically. In addition, effects of carrageenan and lymph node cell transfer against Cryptococcus infection were investigated. As controls, heterozygous littermates (nu/+mice) and mice of strain ddy (ddy mice) were employed. Each mouse was inoculated intravenously with 10(5) yeast cells of Cryptococcus neoformans suspended in 0.2 ml phosphate-buffered saline. Two mice out of each group were sacrificed at appropriate intervals up to 25 days after inoculation and histopathological sections were prepared from them. They were stained with H & E and by PAS method. Histopathological characteristic in the brain was cyst formation with no cellular response. The brain was more severely in the nu/nu mice than in either the nu/+ ddy mice. In the liver, there was a major difference in histopathological findings between the nu/nu and either of the other groups of mouse. In the nu/nu mice, cyst formation with no cellular response was induced, and on the contrary granuloma formation in the nu/+ and ddy mice. However, the granuloma formation was inhibited in the livers of the nu/+ and ddy mice by administration of carrageenan, and induced in the nu/nu mice be cell transfer. In the spleen and lymph nodes, lesions were severer in nu/nu mice than in either the nu/+ or ddy mice. These results suggested that the fungus' invasiveness of mice was strongly influenced by T-cell dependent mechanism.
    Digital Access Access Options