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- BookAleksandar Videnovic, Birgit Högl, editors.Contents:
Part I
1. Introduction: Sleepy days and restless nights of Parkinson's Disease
2. Regulation of sleep and wake homeostasis
3. Neurochemistry of the sleep-wake cycle in Parkinson's disease
4. Impaired sleep and alertness in Parkinson's disease: what did we learn from animal models?
5. Objective measures of the sleep-wake cycle in Parkinson's disease
6. Subjective assessment of sleep and sleepiness in Parkinson's disease. Part II
7. Excessive daytime somnolence associated with Parkinson's disease
8. Insomnia in Parkinson's disease
9. Sleep-disordered breathing in Parkinson's disease
10. Restless legs syndrome and periodic limb movement disorder in Parkinson's disease
11. REM sleep behavior disorder
12. REM sleep behavior disorder: a pre-motor marker of Parkinson's disease
13. Dysregulation of circadian system in Parkinson's disease
14. Cognition and the sleep-wake cycle in Parkinson's disease
15. Fatigue and sleepiness in Parkinson's disease
16. Impact of surgical therapies on sleep and alertness in Parkinson's disease
17. Future directions.Digital Access Springer 2015 - ArticleBernengo MG, Capella G, de Matteis A, Tovo PA, Zina G.Clin Exp Immunol. 1979 May;36(2):279-84.The in vitro effect of a calf thymus extract (TP-1) on peripheral blood lymphocytes was evaluated in sixty-six melanoma patients. Twenty out of forty-five stage I and seventeen out of twenty-one stage IIb patients presented depressed T lymphocyte values. A statistically significant increase in E-rosette-forming cells (E-RFC) was observed in seventeen (85%) stage I and twelve (70.5%) stage II patients. In thirteen (65%) stage I and eight (47%) stage II patients E-RFC reached normal values. Our results indicate that the fall of T lymphocytes in the peripheral blood of melanoma patients is often related to an increase in TP-1 sensitive cells which suggests the possibility of a thymic hormone deficiency in these patients.