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  • Book
    Katrin Scheinemann, Eric Bouffet, editors.
    Contents:
    1. Introduction
    2. Epidemiology of pediatric brain tumors
    3. Clinical signs and symptoms of pediatric brain tumors
    4. Neuro-imaging
    5. Neuro-surgery
    6. Low grade glioma
    7. High grade glioma
    8. Medulloblastoma/ PNET
    9. Ependymoma
    10. Germ cell tumors
    11. ATRT
    12. Craniopharyngeoma
    13. Rare brain tumors (CPP, CPC etc.)
    14. Infant brain tumors
    15. Radiotherapy
    16. Chemotherapy
    17. Targeted treatment
    18. Long term sequelae
    19. Neurocognitive outcome
    20. Quality of life
    21. Palliative care
    22. Cancer syndromes
    23. Brain tumor stem cells
    24. Pediatric neurooncology in developing countries
    25. Neuropathology 26. HDCT/ ASCT
    27. Developmental neurobiology
    28. Basic science of pediatric brain tumors.
    Digital Access Springer 2015
  • Article
    Khan AR.
    Acta Physiol Scand. 1979 May;106(1):69-73.
    The effects of diethyl-stilboestrol (DES), one of the most potent estrogens, were studied on single muscle fibres of the frog. In relatively low concentrations (5 muM), DES greatly potentiates the twitch response of the fibre without significantly affecting the amplitude of the tetanus response. The twitch potentiation is accompanied by an increase in time to peak tension and marked prolongation of the relaxation phase. In tetanic response the half decay time after the last stimulus is also prolonged by DES. DES causes no changes in the resting or action potential of the muscle fibre. The S-shaped curve relating peak contracture tension and caffeine concentration is shifted towards lower caffeine concentrations by DES. Dantrolene greatly suppresses the DES potentiated twitch. It is concluded that DES potentiates the twitch response and prolongs the relaxation time by inhibition of the calcium re-uptake by the sarcoplasmic reticulum.
    Digital Access Access Options