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  • Book
    David A. Hilton, Aditya G. Shivane.
    Summary: This book provides the reader with an up-to-date, practical and succinct overview of basic neuropathology. It does not replace large reference textbooks in neuropathology but emphasizes key concepts and basic principles including recent advances, genetics and classification, and discusses important aspects of specific neuropathological disorders. It also gives practical hints on aspects of neuropathology, including how to best use the neuropathology service and interpret the results of pathological tests. The reader will gain a sufficiently broad basic knowledge of neuropathology which will be of use in their future clinical careers.Neuropathology Simplified is aimed at trainees and residents in neurology, neurosurgery and psychiatry around the world. It may also be of use to basic scientists involved in neuroscience research and also to general histopathology trainees and residents.

    Contents:
    Normal Histology and Commonly Used Stains
    Basic Pathologic Reactions
    Requesting and Interpreting Pathological Tests
    Vascular Diseases
    Infections
    Tumours of Nervous System
    Demyelinating Diseases
    Epilepsy
    Skeletal Muscle Diseases
    Peripheral Nerve Diseases
    Metabolic, Toxic and Nutritional Diseases
    Neurodegenerative Diseases
    Trauma
    Paediatric Diseases
    Autopsy.
    Digital Access Springer 2015
  • Article
    Briaud B, Enjalbert A, Mialhe C, Kordon C.
    Neuroendocrinology. 1979;28(6):371-6.
    Subcellular fractionation of the mediobasal hypothalamus (MBH) and frontal cerebral cortex was performed by differential and discontinuous sucrose gradient centrifugation. Corticotropin-releasing factor (CRF) activity of the different fractions was evaluated by bioassay. Significant CRF activity was found in acidic extracts of the MBH but not of the cerebral cortex. About 80% of the MBH effect on adrenocorticotropic hormone release was recovered in the crude mitochondrial pellet (P2) which contains synaptosomes. After further fractionation, distribution of CRF activity paralleled that of lactate dehydrogenase activity, a marker of the soluble cytoplasm. It is concluded that most CRF in the MBH is located in nerve endings as already shown for several other neurohormones.
    Digital Access Access Options