Today's Hours: 8:00am - 6:00pm
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Book
    Riemer H.J.A. Slart, René A. Tio, Philip H. Elsinga, Markus Schwaiger, editors.
    Summary: This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed. Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.

    Contents:
    Introduction
    Autonomic nervous system of the heart
    Pathophysiology of the autonomic nervous system of the heart
    Tracers for Presynaptic Cardiac Innervation
    Tracers of Adrenergic Receptors
    Tracers of the Parasympathetic System
    Radiopharmaceuticals production under GMP
    Physics of PET-CT and SPECT-CT
    Kinetics & software PET
    SPECT-CT imaging of autonomic innervation in heart diseases
    PET-CT imaging of autonomic innervation in heart diseases
    Imaging ischemic heart disease
    Imaging diabetes mellitus
    Imaging heart failure
    Imaging amyloidosis
    Imaging heart transplantation
    Imaging ventricular arrhythmias
    Guided therapy & imaging
    Imaging the functional brain-heart axis: neurodegenerative diseases
    Imaging the functional brain-heart axis: mental stress & anxiety
    Imaging cardiotoxicity: the effects of chemo- and mono-clonal antibody therapy on autonomic innervation
    Imaging cardiotoxicity: the effect of radiotherapy on autonomic innervation
    Summary and Future Perspectives: PET-MRI Imaging of cardiac Innervation, fluorescence imaging of cardiac innervation
    Epilog
    Index.
    Digital Access Springer 2015
  • Article
    Stulz PM, Scheidegger D, Drop LJ, Lowenstein E, Laver MB.
    J Thorac Cardiovasc Surg. 1979 Aug;78(2):185-94.
    We have compared indices of ventricular function during rapid transfusion of citrated (1.5 ml/kg/min) or heparinized (1.5 ml/kg/min) autologous blood in six patients following discontinuation of cardiopulmonary bypass. Infusion of citrated blood was associated with a lowering of plasma ionized calcium concentration ([Ca++], from 0.90 +/- 0.04 to 0.71 +/- 0.4 mM, p less than 0.001) and an increase in pulmonary artery balloon-occluded pressure (PA0, from 9.4 +/- 2.6 to 15.5 +/- 1.7 mm Hg, p less than 0.u1), without a change in left ventricular stroke work index, stroke index, or cardiac index. Transfusion of heparinized blood caused no change in plasma [Ca++]. A rise in PA0, which was similar in magnitude to that observed during citrated blood transfusion, was associated with increased left ventricular stroke work index, stroke index, cardiac index, and mean arterial pressure. Although data obtained during citrated blood transfusion suggest the presence of transient left ventricular dysfunction, its magnitude is not readily expressed in terms of ventricular function curves when accompanied by a simultaneous change in [Cized closed-chest dog by volume loading during hypocalcemia, when mean arterial pressure, heart rate, and [Ca++] were in a steady state, both prior to and following beta blockade with propranolol. Function curves obtained during severe hypocalcemia ([Ca++] = 0.43 +/- 0.02 mM) were shifted significantly to the right and downward, when compared to those obtained during normocalcemia ([Ca++] = 1.06 +/- 0.03 mM). Hypocalcemia combined with beta blockade resulted in severe left ventricular failure, as demonstrated by a flat ventricular function curve.
    Digital Access Access Options