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  • Book
    authors, Jay M. Weiss, Lyn D. Weiss, Julie K. Silver ; illustrator, Dennis J. Dowling.
    Contents:
    What is an EMG?
    Why perform electrodiagnostic studies?
    About the machine
    Nerve conduction studies
    Electromyography
    Injuries to peripheral nerves
    How to plan out the examination
    Pitfalls
    Carpal tunnel syndrome
    Ulnar neuropathy
    Radial neuropathy
    Radiculopathy
    Spinal stenosis
    Fibular (peroneal) neuropathy
    Tarsal tunnel syndrome
    Peripheral polyneuropathy
    Myopathy
    Brachial plexopathies
    Lumbosacral plexopathies
    Motor neuron diseases
    Critical illness neuropathy and myopathy
    Inflammatory neuropathies
    Neuromuscular junction disorders
    How to write a report
    Tables of normals
    Reimbursement
    Figures for table 4.3 (nerve conduction studies setup)
    Figures for table 5.4 (common muscles: innervation, location, and needle placement).
    Digital Access ScienceDirect 2016
  • Article
    Dennis MJ, Sargent PB.
    J Physiol. 1979 Apr;289:263-75.
    1. The extrasynaptic acetylcholine sensitivity of frog cardiac ganglion cells was measured both after denervation and during the early stages of reinnervation by preganglionic axons. Sensitivity was measured by ionophoretic application of acetylcholine (ACh) to randomly chosen sites on ganglion cell bodies. 2. Extrasynaptic sensitivity rose gradually following denervation and after 3 weeks reached a mean value of approximately 1000 mV/nC. 3. Reinnervation of the cardiac ganglion began about 3 weeks after nerve crush. The ACh sensitivity of ganglion cells fell markedly during the 23--31 day period, to a mean of 184 mV/nC. None of forty-three neurones studied during that period received synaptic inputs sufficient to generate action potentials. 4. Twenty-nine of the forty-three neurones examined 23--31 days after nerve crush had not yet received detectable synaptic inputs, yet even these cells had markedly reduced ACh sensitivity. 5. When reinnervation of cardiac ganglia was delayed by resecting the preganglionic nerves, ACh sensitivity was reduced slightly (43%) between 14--21 and 23--31 days after surgery. Thus, most of the sixfold reduction in sensitivity that occurs during this time after nerve crush is a specific effect of reinnervation. 6. We conclude that loss of extrasynaptic receptors coincides with, or may even precede, the earliest physiological signs of synapse formation. Restoration of action potential activity in the ganglion cells is not essential to initiate this loss.
    Digital Access Access Options