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- Bookedited by Teresa Whei-Mei Fan and Richard M. Higashi, Andrew N. Lane.Contents:
Introduction to metabolomics / Teresa Whei-Mei Fan, Andrew N. Lane, and Richard M. Higashi
Considerations of sample preparation for metabolomics investigation / Teresa Whei-Mei Fan
Clinical aspects of metabolomics / Michael Bousamra II [and others]
Structural mass spectrometry for metabolomics / Richard M. Higashi
Metabolomic applications of inductively coupled plasma-mass spectrometry (ICP-MS) / Rob Henry and Teresa Cassel
Principles of NMR for applications in metabolomics / Andrew N. Lane
Novel NMR and MS approaches to metabolomics / Ian A. Lewis [and others]
Metabolic flux analysis / Tae Hoon Yang
Introduction to metabolic control analysis (MCA) / Maliackal Poulo Joy [and others]
Application of tracer-based metabolomics and flux analysis in targeted cancer drug design / Marta Cascante, Vitaly Selivanov, and Antonio Ramos-Montoya
Noninvasive fluxomics in mammals by nuclear magnetic resonance spectroscopy / Justyna Wolak [and others]
Compositional analysis of phospholipids by mass spectrometry and phosphorus-31 nuclear magnetic resonance spectroscopy / M. Cecilia Yappert
HumanCyc pathway-genome database and pathway tools software as tools for imaging and analyzing metabolomics data / Pedro Romero
Metabolomics-edited transcriptomics analysis (META) / Teresa Whei-Mei Fan.Digital Access Springer 2011 - ArticleTarhan S, White RD, Raimundo HS.Ann Thorac Surg. 1979 Apr;27(4):376-89.Between 1964 and 1978, aortocoronary bypass graft procedures were performed in more than 300,000 patients, and the number seems to increase every year. Nevertheless, the procedure itself can result in perioperative myocardial infarction leading to death. Greater understanding of and constant attention to the myocardial oxygen (O2) supply and demand may reduce the incidence of perioperative myocardial infarction. Some of the factors influencing supply and demand can be controlled pharmacologically. Drugs such as nitroglycerin, nitroprusside, and propranolol can reduce the myocardial O2 demand. Unfortunately, there are few data to elucidate the relationship between myocardial O2 demand and supply as influenced by anesthetic drugs, especially in patients with myocardial ischemia. However, enthusiasm for aortocoronary bypass graft operations has given enormous impetus to laboratory and clinical studies of this subject. Recent developments in anesthetic management afford better means for protection of the ischemic myocardium during and after operation.