BookVasilis Vasiliou, Samir Zakhari, Helmut K. Seitz, Jan B. Hoek, editors.
Summary: In recent years, a significant amount of research has emerged connecting the link between alcohol and cancer. The field has rapidly advanced, especially since the complex connection between alcohol and cancer has several unique sub areas that are being investigated and this volume gives a comprehensive overview of these advancements.
Contents:
Introduction / Gary J. Murray
Alcohol and breast cancer: reconciling epidemiological and molecular data / Samir Zakhari and Jan B. Hoek
Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking / C.J. Peter Eriksson
Alcohol and cancer: an overview with special emphasis on the role of acetaldehyde and cytochrome P450 2E1 / Helmut K. Seitz and Sebastian Mueller
Implications of acetaldehyde-derived DNA adducts for understanding alcohol related carcinogenesis / Silvia Balbo and Philip J. Brooks
The role of iron in alcohol-mediated hepatocarcinogenesis / Sebastian Mueller and Vanessa Rausch
Alcoholic cirrhosis and hepatocellular carcinoma / Felix Stickel
TLR4-dependent tumor-initiating stem cell-like cells (TICS) in alcohol-associated hepatocellular carcinogenesis / Keigo Machida, Douglas E. Feldman, and Hidekazu Tsukamoto
Synergistic toxic interactions between CYP2E1, LPS/TNF[alpha] and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury / Arthur I. Cederbaum, Yongke Lu, Xiaodong Wang, and Defeng Wu
Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinoma / Colin T. Shearn and Dennis R. Petersen
Alcohol consumption, WNT/[beta]-Catenin signaling and hepatocarcinogensis / K.E. Mercer, L. Hennings, and M.J.J. Ronis
Alcohol and HCV: implications for liver cancer / Gyongyi Szabo, Banishree Saha, and Terence N. Bukong
Application of mass spectrometry-based metabolomics in identification of early noninvasive biomarkers of alcohol-induced liver disease using mouse model / Soumen K. Manna, Matthew D. Thompson, and Frank J. Gonzalez
Alcohol metabolism by oral streptococci and interaction with human papillomavirus leads to malignant transformation of oral keratinocytes / Lin Tao, Sylvia I. Pavlova, Stephen R. Gasparovich, Ling Jin, and Joel Schwartz
Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers / Akira Yokoyama, Takeshi Mizukami, and Tetsuji Yokoyama
Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers / S. Singh, J. Arcaroli, D.C. Thompson, W. Messersmith, and V. Vasilou
Alcohol, carcinoembryonic antigen processing and colorectal liver metastases / Benita McVicker, Dean J. Tuma, Kathryn E. Lazure, Peter Thomas, and Carol A. Casey
Alcohol consumption and antitumor immunity: dynamic changes from activation to accelerated deterioration of the immune system / Hui Zhang, Zhaohui Zhu, Faya Zhang, and Gary G. Meadows
A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma / Sangeeta Shrotriya, Rajesh Agarwal, and Robert A. Sclafani
The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis / Clay Smith, Maura Gasparetto, Craig Jordan, Daniel A. Pollyea, and Vasilis Vasiliou
The effect of alcohol on Sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC) / Kyle J. Thompson, John R. Humphries, David J. Niemeyer, David Sindram, and Iain H. McKillop
Transgenic mouse models for alcohol metabolism, toxicity and cancer / Claire Heit, Hongbin Dong, Ying Chen, Yatrik M. Shah, David C. Thompson, and Vasilis Vasiliou
Fetal alcohol exposure increases susceptibility to carcinogenesis and promotes tumor progression in prostate gland / Dipak K. Sarkar
Fetal alcohol exposure and mammary tumorigenesis in offspring: role of the estrogen and insulin-like growth factor systems / Wendie S. Cohick, Catina Crismale-Gann, Hillary Stires, and Tiffany A. Katz.
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