Bookvolume editors, Edith V. Sullivan and Adolf Pfefferbaum.
Summary: "Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism"--Publisher's description.
Contents:
Section 1. Introduction
Alcoholism: diagnosis, prognosis, epidemiology, and burden of the disease / Thomas Beresford
Perspectives on the neuroscience of alcohol from the National Institute on Alcohol Abuse and Alcoholism / Kenneth Warren and Matthew Reilly
Section 2. Animal models: neurochemistry and metabolism of alcohol
Neurocircuitry of alcoholism: synthesis from animal models / George F. Koob
Metabolism / David Crabb and Martin Plawecki
Use of animal models of alcohol-related behavior / John C. Crabbe
Section 3. Molecular basis of alcoholism
Molecular basis of alcoholism / Dana Most, Laura Ferguson and R Adron Harris
Section 4. Neurological signs and consequences
Alcohol: intoxication and poisoning: diagnosis and treatment / Young-Chul Jung
Acute withdrawal: diagnosis and treatment / John CM Brust
Neurochemical mechanisms of alcohol withdrawal / Howard C. Becker
Molecular and neurological responses to chronic alcohol use / Michael F. Miles
Section 5. Neuropsychology
Methods of association and dissociation for establishing selective brain-behavior relations / Rosemary Fama and Edith V. Sullivan
Profiles of impaired, spared, and recovered neuropsychological processes in alcoholism / Marlene Oscar-Berman
Component processes of memory in alcoholism: pattern of compromise and neural substrates / Anne-Lise Pitel and Helene Beaunieux
Decision making, risky behavior, and alcoholism / George Fein
Motor systems and postural instability / Jessica Rose
Sex differences in alcohol-related neurobehavioral consequences / Sara Jo Nixon
Section 6. Neuroimaging of brain macrostructure and microstructure
Structural and microstructural imaging of the brain in alcohol use disorders / Natalie May Zahr
Section 7. Neuroimaging of neurochemical markers
Molecular imaging in alcohol dependence / Annisa Abi-Dargham
Brain proton magnetic resonance spectroscopy of alcohol use disorders / Dieter Meyerhoff
Section 8. Neuroimaging of brain function
Cognition, emotion, and attention / Tilman Schulte and Eva Muller-Oehring
The neurobiology of alcohol craving and relapse / Rajita Sinha
Compensatory recruitment of neural resources in chronic alcoholism / Sandra Chanraud
Section 9. Neuroelectrophysiology
Understanding alcohol use disorders with neuroelectrophysiology / Bernice Porjesz
Sleeping eeg / Ian Colrain
Section 10. Fetal alcohol spectrum disorder
Neurobehavioral, neurological, and neuroimaging characteristics of fetal alcohol spectrum disorders / Leila Glass, Ashley L. Ware and Sarah Mattson
Fetal alcohol spectrum disorder: pathogenesis and mechanisms / Kathleen Sulik
Current hypotheses on the mechanisms of alcoholism / Fulton Crews
Section 11. Adolescent drinking
The effect of alcohol use on human adolescent brain structures and systems / Susan F. Tapert
Section 12. Other topics
Peripheral systems: neuropathy / Robert O. Messing and Rajani Maiya
Pharmacological treatment of alcoholism / Raymond Francis Anton
Alcohol-medical drug interactions / Bankole A. Johnson and Chamindi Seneviratne
Genetics of alcoholism / Howard J. Edenberg
Co-occurring psychiatric disorders and alcoholism / J Stephen Rich and Peter R. Martin
Hepatic encephalopathy in alcoholic cirrhosis / Roger F. Butterworth
Neuropathology of alcoholism / Jillian Kril
Genetic differences in response to alcohol / Sachio Matsushita and Susumu Higuchi
Epidemiology of drinking, alcohol use disorders, and related problems / Raul Caetano, Patrice A.C. Vaeth, Karen Chartier and Britain A. Mills
Alcohol and the law / Michael J. Ostacher
Clinical management of alcohol use disorders in the neurology clinic / Anna Lembke and Mark Stanford.