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- BookDavid M. Parham, Joseph D. Khoury. M. Beth McCarville, editors.Summary: Pediatric Malignanies: Pathology and Imaging serves as a state-of-the-art reference for understanding the fundamental biology and diagnostic aspects of pediatric tumors. This volume stands apart from other books covering pediatric neoplasia by providing an in-depth analysis of the pathogenetic and diagnostic aspects of the most commonly encountered tumors. The volume covers the new advances in our understanding of the molecular processes underlying a number of pediatric tumors and the novel, sophisticated diagnostic tools that have now become an integral part of practice standards. Pediatric Malignanies: Pathology and Imaging will be of great value for practicing clinicians, oncologists, radiologists, surgeons, pediatricians and pathologists for characterizing and diagnosing childhood tumors.
Contents:
Laboratory Techniques Used in the Diagnosis of Pediatric Tumors
Imaging Techniques Used in the Diagnosis of Pediatric Tumors
Soft Tissue Sarcomas
Malignant Bone Tumors
Tumors of Lymphoid and Hematopoietic Tissues
Tumors of the Central Nervous System
Pediatric Cancer in the Head and Neck
Malignancies of the Pediatric Lower Respiratory Tract
Gastrointestinal Cancers in Children
Malignant Renal Tumors
Germ Cell and Gonadal Tumors
Tumors of the Adrenal Gland
Malignant Skin Tumors in Children
Intraocular Tumors
Malignant Tumors of Peripheral Nerves. - ArticleWilliams JE, Cavanaugh DC.Bull World Health Organ. 1979;57(2):309-13.The relationship of F1 antibody titre to protection against plague was investigated by subjecting seropositive laboratory rats to virulent challenge and observing for survival. The passive haemagglutination (PHA) test in microtitre was employed for serology. Rats vaccinated with live vaccine EV76 (51f), killed U.S.P. vaccine, or F1 antigen and challenged by subcutaneous inoculation of 1 x 10(3) to 5 x 10(5)Yersinia pestis survived at similar rates that, overall, equalled 6% at titres less than 1:16, 46% at titres of 1:32-1:64, 90% at titres of 1:128-1:256, and 96% at titres of 1:512-1:1024. Rats vaccinated with F1 antigen and rats that had been infected previously were challenged intranasally with 8.9 x 10(4)Y. pestis and subsequently demonstrated similar rates of survival that was zero at titres less than 1:128, 86% at titres of 1:128-1:256, and 100% at titres of 1:512-1:1024. The significance of titre of F1 antibody as a measure of seroimmunity against acute bubonic or pneumonic plague is discussed for rats, monkeys, and man.