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  • Book
    Vijay C. Verma, Alan C. Gange, editors.
    Summary: In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.

    Contents:
    Part 1: Ecology and Biodiversity
    Chapter 1. Diversity and ecology of endophytic and epiphytic fungi of tree leaves in Japan: a review
    Chapter 2. Endophytic actinobacteria: diversity and ecology
    Chapter 3. Foliar fungal endophytes in herbaceous plants: a marriage of convenience?
    Part 2: Entomopathogenic endophytes
    Chapter 4. Entomopathogenic and nematophagous fungal endophytes
    Part 3: Host-endophyte interactions
    Chapter 5. Interactions of meristem-associated endophytic Bacteria
    Chapter 6. Unraveling the dark septate endophyte functions: Insights from the Arabidopsis model
    Chapter 7. Asexual endophytes of grasses: Invisible symbionts, visible imprints in the host neighborhood
    Part 5: Bioactive compounds from endophytes
    Chapter 8 . Microbial endophytes their resilience for innovative treatment solution to neglected tropical diseases
    Chapter 9. Endophytes and plant secondary metabolite synthesis: molecular and evolutionary perspective
    Chapter 10. Endophytes as a novel source of bioactive new structures
    Chapter 11. Host-mimetic metabolomics of endophytes: looking back into the future
    Chapter 12. Myconanosynthesis: Redefining the role of microbial endophytes
    Part 6: Bio-control and bioremediation
    Chapter 13. Biological control of insect-pest and diseases by?endophytes
    Chapter 14. Biocontrol and bioremediation: two areas of endophytic research which hold great promise
    Chapter 15. Biosourcing endophytes as biocontrol agents of wilt diseases.-Chapter 16. Ecology and functional potential of endophytes in bioremediation: a molecular prospective
    Chapter 17 Ecological aspects of endophyte-based biocontrol of forest diseases
    Chapter 18 Endophyte mediated biocontrol of herbaceous and non-herbaceous plants
    Part 7: Endophytes and cancer
    Chapter 19. Implication of endophytic metabolite and their derivatives in cancer chemotherapy: a prospective study
    Chapter 20. Endophytic fungi: novel sources of anticancer molecules
    Part 8: Future challenges
    Chapter 21. A functional view of plant microbiomes: Endosymbiotic systems that enhance plant growth and survival
    Chapter 22. Microbial endophytes: future challenges.
    Digital Access Springer 2014
  • Article
    Michałkiewicz J.
    Arch Immunol Ther Exp (Warsz). 1978;26(1-6):801-5.
    The investigation has been carried out on 30 patients with rheumatoid arthritis. Rosettes (E, EA, EAC) technique and immunofluorescence test were used to detect the surface markers of lymphocytes. Cytotoxic activity of T and K cells in vitro was established. It has been proved that cells occurred to a larger extend in synovial fluid than in the peripheral blood. B cells and lymphocytes with Fc receptors were only a few in synovial fluid. The percentage ofFc receptors bearing cells was higher in the peripheral blood of patients with rheumatoid arthritis than that in peripheral blood of the control group. Cytotoxic activity of K-cell was low in synovial fluid. PHA-cell mediated cytotoxicity was low in peripheral blood as well as in synovial fluid of patients with rheumatoid arthritis.
    Digital Access Access Options