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  • Book
    Kewal K. Jain.
    Summary: Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various -omics technologies and their application in oncology are described as oncogenomics and oncoproteomics. This detailed volume also explores molecular diagnostics, nanobiotechnology, cell and gene therapies, as well as personalized oncology. With approximately one thousand selected references from recent literature on this topic and numerous tables and figures, Applications of Biotechnology in Oncology serves as an ideal reference for oncologists, scientists involved in research on cancer biology, and physicians in various specialties who deal with cancer.

    Contents:
    1. Molecular biology of cancer
    2. Oncogenomics
    3. Sequencing in cancer
    4. Oncoproteomics
    5. Biomarkers of cancer
    6. Molecular diagnosis of cancer
    7. Cancer immunotherapy : vaccines
    8. Monoclonal antibodies and cancer
    9. Nanooncology
    10. Cell therapy of cancer
    11. Gene therapy of cancer
    12. Role of RNAi in cancer
    13. Role of microRNAs in cancer
    14. Biotechnology in drug discovery and development for cancer
    15. Role of biotechnology in drug delivery for cancer
    16. Personalized cancer therapy.
    Digital Access Springer 2014
  • Article
    Mizerski J, Noworolski J, Zembala M.
    Arch Immunol Ther Exp (Warsz). 1978;26(1-6):411-5.
    The effect of the lymphocytes from picryl sulfonic acid treatment animals on primary and secondary humoral immune response to TNP hapten was investigated. These cells known to inhibit contract sensitivity reactions were also able to depress primary IgM response. When peritoneal exudate cells from normal mice incubated in suppressor supernatant were transferred into primed mice the suppression of IgM but no IgM secondary response was observed. In contrast peritoneal exudate cells incubated in control supernatant augmented IgM but didn't affect IgG response. It is postulated that normal peritoneal exudate cells (presumably macrophages) can stimulate IgM response. This enhancing activity could be partially blocked by soluble suppressor factor.
    Digital Access Access Options