Search

Search Results

• Book

  Antimicrobial compounds : current strategies and new alternatives

  Tomás G. Villa, Patricia Veiga-Crespo, editors.

  Summary: Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
  
  Contents:
  Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining
  X-ray and Neutron Scattering Foundations for the Research in Antimicrobials
  Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications
  New antimicrobial agents of plant origin
  Advances in beta-lactam antibiotics
  The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria
  Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds
  Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB)
  New cell wall-affecting antifungal antibiotics
  Perspectives in the research on Antimicrobial peptides
  Glycopeptides and bacterial cell walls.

  Digital Access Springer 2014
  Get Shareable Link

  View Details
• Article

  PABA-Test versus Chymotrypsin- und Fettbestimmung im Stuhl in der Pankreasfunktionsdiagnostik. [PABA test versus chymotrypsin and fat determinations in the stool in pancreatic functional diagnosis].

  Bühler H, Ammann R.

  Schweiz Med Wochenschr. 1979 Apr 21;109(16):597-8.

  32 patients with proven chronic pancreatitis and 56 controls without evidence of pancreatic disease were studied by the PABA test, the fecal chymotrypsin method and the fecal fat method. The sensitivity of the fecal chymotrypsin method for detection of pancreatic disease was significantly higher (p less than 0.005). The sensitivity of the PABA test and the fecal fat method were comparable. The specificity of the PABA test and the fecal chymotrypsin method was of the same order.

  Digital Access Access Options
  Get Shareable Link

  PubMed