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  • Book
    Jørgen Kjems, Elena Ferapontova, Kurt V. Gothelf, editors.
    Summary: This volume on nucleic acid nanotechnology offers authoritative, up-to-date and comprehensive coverage of nanotechnological studies and applications of nucleic acids. It provides reviews of various aspects of nucleic acid nanotechnology, each written by an internationally leading expert in the field, and presents state-of-the-art and recent advances in nucleic acid synthetic modifications, nanoscale design, manipulation and current and future applications in bioengineering, medicine, electronics, genetic analysis, chemistry, molecular biology, surface and material sciences. It examines how nucleic acid research is merging with nanotechnology, allowing the nanoscale properties of nucleic acid to be exploited in performing challenging nanotechnological tasks, from nanorobotics and nanosensing to nucleic acid computing. This book will above all benefit anyone who is interested in nanotechnological concepts of nucleic acid design and applications, and offers a valuable resource for teaching these concepts. It is essential reading for a broad audience of scientists both in academia and industry who wish to expand their expertise on the potential of nucleic acid functions and applications.

    Contents:
    Self-assembly of DNA bases via hydrogen bonding studied by Scanning tunneling microscopy
    Force spectroscopy of DNA and RNA: structure and kinetics from single molecule experiments
    The power of single molecule FRET microscopy applied to DNA nanotechnology
    DNA nanostructures: DNA Tiles
    DNA Origami
    DNA nanotechnology: From biology and beyond
    DNA Templated Synthesis
    Mechanical DNA devices
    Nano-encapsulation of Oligonucleotides for Therapeutic Use
    Cell-specific aptamers for nano-medical applications
    Nucleic acid sequencing and analysis with nanopores
    Application of Nanomaterials For DNA Sensing.
    Digital Access Springer 2014
  • Article
    Vidne BA, Nili M, Aygen M, Levy MJ.
    Scand J Thorac Cardiovasc Surg. 1979;13(1):37-40.
    Three patients with the rare anomaly of congenital absence of the ostium of the left main coronary artery are presented. In two of the patients, aged 50 and 52 respectively, the diagnosis was established during selective coronary cineangiography for a severe anginal syndrome. The third patient, a 16-year-old-girl, underwent cardiac catheterization for investigation of a congenital heart malformation, when a single right coronary artery was demonstrated with absence of the main coronary artery ostium. Two patients underwent successful aortocoronary bypass grafting. In view of the occurrence of sudden death and massive myocardial infarction in adult patients shown to have severe or complete obstruction of the left main coronary artery, it is suggested that adult patients with this condition, who require open-heart surgery for any other cardiac disorder, should undergo aortocoronary bypass grafting concurrently even prior to the development of anginal symptoms. Children shown to have this anomaly should be subjected to long-term follow-up and have an aortocoronary bypass graft performed when symptoms of coronary insufficiency develop.
    Digital Access Access Options