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  • Book
    Kok-Yang Tan, editor.
    Summary: This book discusses in depth the transdisciplinary integration of different components of care in colorectal surgery. Pertinent background information on the complexities of current management in colorectal surgery is first provided, followed by discussion of the role of design thinking in care integration. Subsequent chapters focus on a range of issues associated with surgical and perioperative care in patients undergoing colorectal surgery, with emphasis on how the multiple facets of care can be integrated through a transdisciplinary approach. Each chapter provides helpful take-home messages in bullet point form and numerous informative figures and tables are also included. The authors are surgeons, physicians, anesthetists, oncologists, nurses, and allied health professionals with extensive experience in the field.

    Contents:
    Complexity of Current Healthcare and Transdisciplinary Care
    Design Thinking in Care Integration
    Integrative Care for Elderly Patients
    Integrative Perioperative Nutrition
    Transdisciplinary Nursing
    Enhanced Recovery
    Integrative Pharmacology
    Transdisciplinary Prehabilitation and Rehabilitation
    Transdisciplinary Cancer Management
    Marrying Endoscopic and Laparoscopic Treatment for Colorectal Cancer
    Multimodal Approach to Familial Colorectal Cancer
    Transdisciplinary Incontinence Management
    Transdisciplinary Constipation Management
    Innovations in Perianal Care and Surgery
    Transdisciplinary Stoma Care
    Healing and Psychosocial Issues.
    Digital Access Springer 2015
  • Article
    Schechter B, Feldman M.
    Naturwissenschaften. 1979 Mar;66(3):140-6.
    The role of immunosuppressor cells in preventing host immune rejection of tumor cells is described. The growth of Lewis lung carcinoma (3LL) in syngeneic C57BL mice is accompanied by a weak and transient anti-tumor cytotoxic response that is later on replaced by tumor-enhancing activity. This enhancing activity is correlated with the generation of suppressor cells in 3LL-bearing mice. Such suppressors were demonstrated in two ways: (a) Elimination of the hydrocortisone(HC)-sensitive lymphoid population from tumor-bearing mice (TBM) resulted in a significant increase in the anti-tumor cytotoxic response and in a marked delay in tumor development. It is assumed that HC inactivates precursors of suppressor lymphocytes whereas the mature suppressor cells themselves are HC-resistant. (b) The increased resistance against the tumor could be partially re-suppressed by restoring the HC-treated TBM with spleen or thymus cells from normal C57BL. Suppression, however, was more pronounced if the resistant mice were restored with spleen or thymus cells from TBM. HC-resistant spleen cells from TBM that appear to be enriched for mature suppressor cells were capable of suppressing in vitro the secondary sensitization of spleen cells from TBM against tumor cells.
    Digital Access Access Options