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  • Book
    Florian Otto, Manfred P. Lutz, editors.
    Summary: "This Recent Results in Cancer Research volume provides an up-to-date overview of the multidisciplinary management of locally confined rectal cancer as well as colorectal cancer with synchronous resectable liver metastases. The contents comprise the majority of the invited contributions from the Second St. Gallen EORTC Gastrointestinal Cancer Conference, held on 6-8 March 2014 in St. Gallen, Switzerland. Written by some of the world's leading experts in the imaging, endoscopy, pathology, molecular biology, surgery, radiotherapy, and medical oncology of rectal cancer and liver metastases, the chapters offer a comprehensive view on the latest recommendations in diagnosis and multidisciplinary treatment. Every clinician involved in the care of patients with rectal cancer will find this book interesting and helpful."--Publisher's description.

    Contents:
    Staging of rectal cancer
    Imaging assessment of early rectal cancer / Jo Waage, Fiona Taylor, James Read and Gina Brown
    Predicting lymph node metastases in pT1 rectal cancer / S. L. Bosch and I. D. Nagtegaal
    Treatment of early rectal cancer
    Endoscopic resection: when is EMR/ESD sufficient? / H. Messmann
    Transanal endoscopic microsurgery /Chris Cunningham
    Surgical treatment of rectal cancer
    What is "good quality" in rectal cancer surgery? The pathologist's perspective / S. L. Bosch and I. D. Nagtegaal
    Total mesorectal excision: open, laparoscopic or robotic / Monica Young and Alessio Pigazzi
    Ultra low resection versus abdomino-perineal excision in low rectal cancer / Torbjörn Holm
    T4 rectal cancer: do we always need an exenteration? / Thomas A. Vermeer, Miranda Kusters and Harm J. T. Rutten
    Do T3 rectal cancers always need radiochemotherapy? / Rob Glynne-Jones
    Quality of life after surgery for rectal cancer / Teresa Gavaruzzi, Francesca Giandomenico, Paola Del Bianco, Lorella Lotto, Alessandro Perin and Salvatore Pucciarelli
    Combined modality therapy in rectal cancer
    Aims of combined modality therapy in rectal cancer (M0) / J. P. Gerard, K. Benezery, J. Doyen and E. Francois
    Neoadjuvant radiotherapy (5 3 5 Gy): immediate versus delayed surgery / Krzysztof Bujko, Maciej Partycki and Lucyna Pietrzak
    Early and late toxicity of radiotherapy for rectal cancer /Ines Joye and Karin Haustermans
    Immediate surgery or clinical follow-up after a complete clinical response? / Angelita Habr-Gama and Rodrigo Oliva Perez
    Rectal cancer with synchronous liver metastases
    Limits of colorectal liver metastases resectability: how and why to overcome them? / Serge Evrard
    Rectal cancer with synchronous liver metastases: leave it all in? When (not) to resect the primary? / Florian Lordick
    Recurrence patterns after resection of liver metastases from colorectal cancer / Halfdan Sorbye.
    Digital Access Springer 2014
  • Article
    Horn JR, Kapur JJ, Walker SE.
    Arthritis Rheum. 1978 Jul-Aug;21(6):709-14.
    Mixed connective tissue disease (MCTD) was diagnosed in a brother and sister, and 18 additional family members spanning three generations were studied to detect evidence of autoimmune disease. Symptoms or signs of MCTD without complete expression of the disease were found in 8 relatives of the original cases. Antibodies to ribonucleoprotein and high-titer antinuclear antibodies were found only in the affected siblings. Tests for rheumatoid factor were positive in 9 of 17 relatives of the patients; the titers ranged from 1:160 to 1:2560. The brother and sister with MCTD had an identical HLA genotype--11,12/2,12. The same genotype was inherited by 3 of their siblings, who had impressive rheumatic complaints. This report emphasizes the association between inflammatory connective tissue disease and a specific HLA type within a single kindred.
    Digital Access Access Options