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  • Book
    editor, Bruce Ovbiagele.
    Contents:
    Best practices in neurological care / Bruce Ovbiagele
    Epilepsy / Omotola A. Hope & Jeremy Lankford
    Parkinson's disease / Jori Fleisher & Nabila Dahodwala
    Neuromuscular diseases / Hajime Tokuno, Pooia Fattahi & Huned S. Patwa
    Dementia / Liana G. Apostolova
    Headache / Charles C. Flippen II
    Brain tumor management / Seema Nagpal, Scott G. Soltys, Gordon Li, Griffith Harsh & Lawrence Recht
    Neuroinfectious diseases / David Croteau
    Stroke / Shelly Ozark, Diana Goodman & Christine Holmstedt
    Multiple sclerosis / Lily Jung Henson
    Evidence-based therapies in neurologic rehabilitation / Bruce H. Dobkin & Andrew Dorsch
    Neurocritical care / Paul Vespa & Vikas Grover
    Palliative care in neurology / Eli L. Diamond & Alan C. Carver
    Index.
    Digital Access Future Med 2014
  • Article
    Romagnani S, Amadori A, Giudizi MG, Biagiotti R, Maggi E, Ricci M.
    Immunology. 1978 Sep;35(3):471-8.
    The response to SPA and Staphylococcus strain Cowan I (StaCw) of highly purified populations of peripheral blood and tonsil human lymphocytes was investigated. Purified T lymphocytes isolated from perpheral blood by E-rosetting were unable to respond in vitro to StaCw. Highly purified B-cell populations from tonsils did not show any proliferative response in the presence of soluble SPA. The addition to highly purified B-cell suspensions from human tonsils of increasing concentrations of autologous T lymphocytes did not induce any increase of thymidine uptake in the presence of StaCw. However, it was able to restore a marked proliferative response of the B-cell cultures to soluble SPA, even though mitomycin-treated T lymphocytes were added. The low response of highly purified peripheral blood T lymphocytes to soluble SPA could be potentiated by the addition of autologous mitomycin-treated B cells, whereas the unresponsiveness of purified T lymphocytes to StaCw was not affected. Mitogenic activity of SPA coupled to Sepharose beads was different from that of soluble SPA and paralleled that of StaCw. These data strongly suggest that insoluble SPA is a T-cell-independent B-cell mitogen in man, whereas soluble SPA, like PWM, exerts its activity on B cells only in the presence of T cells.
    Digital Access Access Options