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  • Book
    editor, Ronald M. Bukowski.
    Contents:
    Targeted therapy for renal cell carcinoma / Ronald M. Bukowski
    Overview of renal cell carcinoma pathways and drug targets / Bernard Escudier
    mTOR in renal cell cancer: modulator of tumor biology and therapeutic target / Piotr J. Wysocki
    VEGF inhibitors / Toni K. Choueiri & Ali R. Golshayan
    VEGFR/PDGFR inhibitors in RCC / Jean S.Z. Lee & Tim Eisen
    Next-generation immunotherapy: CTLA-4 and PD-1 inhibitors / Daniel Y.C. Heng
    EGF receptor inhibitors / Marine Gross-Goupil & Alain Ravaud
    Cytokines / Alexandra Leary, James M.G. Larkin & Lisa M. Pickering
    Vaccination / Robert J Amato
    Evidence-based therapy of non-clear-cell and sarcomatoid renal cell carcinoma / Elan Diamond, Naveed H. Akhtar, Scott T. Tagawa & David M. Nanus
    Bisphosphonates in renal cell carcinoma: palliation versus antitumor effects / Saby George & Roberto Pili
    Combination therapy and future directions in renal cell carcinoma / Bernard Escudier & Camillo Porta.
    Digital Access Future Med 2011
  • Article
    Michlmayr G.
    Fortschr Med. 1978 Oct 12;96(38):1928-32.
    In untreated patients with Hodgkin's disease the percentage of T-lymphocytes was significantly reduced in comparison to healthy controls independent of the stage of the disease. The absolute number of T-lymphocytes was also reduced in most patients. The response of lymphocytes after PHA-stimulation was diminished parallel with the skin reactivity: Normal results were obtained in early stages and with favorable histological types whilst low values were found in stages III and IV and in unfavourable histological types. A correlation between the percentage of T-lymphocytes and the PHA-stimulation was found in early stages, but not in stages III and IV. There was also a correlation between the absolute number of T-lymphocytes and skin reactivity. The percentage of DNA-synthesizing lymphocytes was significantly higher than in normal blood. The highest values were found in stages III and IV and in unfavourable histological types. After radiation therapy the T-lymphopenia, the diminished PHA-stimulation as well as anergy was more pronounced than after chemotherapy.
    Digital Access Access Options