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- Bookeditors, Joseph R. Lakowicz, Jian Zhang.Contents:
Emerging applications of colloidal noble metals in cancer nanomedicine / Jian Zhang & Joseph R. Lakowicz
Particle characterizations and synthesis methods / Jian Zhang & Joseph R. Lakowicz
Diagnostics and treatments / Anna M. Sitarski, Jeremy L. Grant, Sanjeev Kumar Kandpal & Michael D. Mason
Photothermal agents for cell theranostics / Dmitri O. Lapotko
Drug delivery carriers / Marie-Christine Daniel
Other applications and future directions / Ismail Ocsoy, Tao Chen & Weihong Tan
Applications of noble metal nanoparticles in fluorescence sensing / Yi Fu
Index. - ArticleWoodland R, Cantor H.Eur J Immunol. 1978 Aug;8(8):600-6.We have tested the proposition that induction of certain sets of B cell clones to produce antibody requires a signal from T helper cells that recognize idiotypic determinants expressed on Ig receptors of the relevant B cell clones. The approach is based on the analysis of T cell populations required to induce B cells to secrete anti-arsonate antibodies that are marked by a cross-reactive idiotype (CRId). crid+ anti-azophenyl arsonate (Ar) antibodies are produced in A/J strain mice after immunization with Ar keyhole limpet hemocyanin and represent 20--70% of the total anti-Ar antibody response. These studies indicate that antibody secretion by idiotype+ B memory cells requires two signals: one provided by "carrier"-specific Ly-1 cells, and a second delivered by idiotype-specific Ly-1 cells. Both signals are required for optimal induction of idiotype+ B memory clones.