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  • Book
    editor, Fortunato Ciardiello.
    Contents:
    EGFR inhibitors in cancer treatment / Fortunato Ciardiello
    Mechanisms of action of EGFR inhibitors / Nicola Normanno, Maria Pergameno, Alessia Iannaccone & Antonella De Luca
    Selection of NSCLC patients to treat with EGFR inhibitors in the era of personalized medicine / Rafael Rosell, Laura Bonanno & Miquel Taron
    Clinical results with EGFR inhibitors in NSCLC and their use in the treatment of metastatic disease / Cesare Gridelli & Antonio Rossi
    Clinical results with EGFR inhibitors in colorectal cancer / Erika Martinelli, Teresa Troiani, Floriana Morgillo & Fortunato Ciardiello
    EGFR-directed therapies in squamous cell carcinoma of the head and neck / Pol Specenier & Jan B. Vermorken
    Optimal use of EGFR inhibitors : challenges, new drugs and future directions / Sara De Dosso, Rodrigo Dienstmann & Josep Tabernero.
    Digital Access Future Med 2011
  • Article
    Collavo D, Engers H, Nabholz M.
    Eur J Immunol. 1978 Aug;8(8):595-9.
    Addition of supernatant from concanavalin A-stimulated spleen cells to in vitro primed cytolytic T lymphocytes in semisolid medium stimulated the growth of colonies of cytolytic lymphocytes. Optimal results were obtained using a peritoneal adherent cell underlayer where a 10% plating efficiency (greater than or equal to 4 cells per colony) was achieved when between 5000 and 100 000 cells were plated per dish. Individual colonies were harvested and tested in a short term (5h) 51Cr release microassay, employing 200 target cells. The frequency of lytic colonies varied from 46--67%. The observed lytic activities were specific for the relevant allogeneic target cells.
    Digital Access Access Options