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  • Book
    Uri Gophna, editor.
    Summary: "Although the phenomenon of lateral gene transfer has been known since the 1940s, it was the genomics era that has really revealed the extent and many facets of this evolutionary/genetic phenomenon. Even in the early 2000s with but a handful of genomes available, it became clear that the nature of microorganisms is full of genetic exchange between lineages that are sometimes far apart. The years following this saw an explosion of genomic data, which shook the "tree of life" and also raised doubts about the most appropriate species concepts for prokaryotes. This book represents the manyfold contributions of LGT to the evolution of micro and, to an extent, macroorganisms by focusing on the areas where it has the largest impact: metabolic innovations and adaptations and speciation." Back cover.

    Contents:
    Part 1. LGT-Driven Metabolic Innovations and Adaptations
    Lateral Gene Transfer and the Synthesis of Thymidine
    Lateral Gene Transfer and the Evolution of Photosynthesis in Eukaryotes
    On the Eco-evolutionary Relationships of Fresh and Salt Water Bacteria and the Role of Gene Transfer in their Adaptation
    Mobilized Integrons: Team Players In The Spread of Antibiotic Resistance Genes
    Plasmids of the bovine Rumen
    Part 2. The Integration of New Genes into Existing Networks
    Lateral Gene Transfer and Cellular Networks
    The Complexity Hypothesis and Other Connectivity Barriers to Lateral Gene Transfer
    How Codon Usage Shapes Gene Transfer and Vice Versa
    Part 3. Inter-domain Gender Transfer
    Lateral Gene Transfer in Animals
    Gene Transfer and the Chimeric Nature of Eukaryotic Genomes
    Gene transfer from Eukaryotes to Legionella
    Application of a new Mapping Algorithm to Reevaluate Evidence of Interdomain Horizontal Gene Transfer in the Genome of Thermotoga Maritime
    Part 4. LGT, Speciation and the Tree/Web of Life
    Gradual Speciation and its Implications for the Tree of Life
    Biased Gene Transfer Contributes to Maintaining the Tree of Life
    Speciation in the Shadow of Recombination and Lateral Gene Transfer
    Index.
    Digital Access Springer 2013
  • Article
    Zola H, Valdimarsson H.
    Br J Haematol. 1978 Aug;39(4):607-14.
    An antiserum with specificity for human T lymphocytes was evaluated as a diagnostic reagent in the clinical immunology laboratory. The antiserum was used in indirect immunofluorescence to detect T cells in blood samples from normal controls and patients with various disorders involving the immune system. The same samples were also examined using two established tests for T cells, the rosette reaction with sheep red blood cells (E rosette assay) and the proliferative response to phytohaemagglutinin (PHA). The antiserum and the rosette assay detected approximately the same numbers of T cells in controls, but the antiserum indicated T cell deficiency in several patients who appeared normal by rosetting or PHA reactivity. PHA stimulation in autologous plasma was depressed in a further group of patients who had normal T cell numbers by the other two tests. In vitro experiments with normal lymphocytes indicated that the E-rosette receptor was distinct from determinants detected by the T-cell specific antiserum. The immunofluorescence test with the anti-T serum provides an additional assay which appears to be more sensitive than the other two tests in detecting certain cases of T lymphocyte deficiency.
    Digital Access Access Options