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- BookJawahar L. Mehta, Naranjan S. Dhalla, editors.Summary: Angiogenesis plays a key role in human physiology and pathophysiology. While necessary for tissue growth and development, uncontrolled angiogenesis plays a role in the progression of certain tumors as well as atherosclerosis. Lack of angiogenesis may be the basis of myocardial ischemia and stroke. Knowledge on the mechanisms of angiogenesis is growing very rapidly, and may lead to important drugs for therapy of a variety of clinical disorders. Experts from around the world have contributed a vast array of data on different aspects of angiogenesis in this volume edited by Professors Mehta and Dhalla. This information will be of immense help to basic scientists, clinicians and those involved in drug development.
Contents:
Molecular Mechanisms of Angiogenesis. Endothelial Growth Factor Receptors in Angiogenesis / David J. Bruce, Peng H. Tan
Role of Transforming Growth Factor Beta in Angiogenesis / Alicia Viloria-Petit ... [et al.]
Role of Cytokines in Angiogenesis: Turning It On and Off / Melissa A. Thal, Raj Kishore
Neuropeptides and Angiogenesis / Leena Pradhan-Nabzdyk, Christoph Nabzdyk
Role of Integrins in Angiogenesis / Ghazaleh Tabatabai, Michael Weller
Regulation of Angiogenesis by Hypoxia-Inducible Factors / Hideki Hayakawa, Futoshi Shibasaki
Role of Mast Cells in Angiogenesis / Enrico Crivellato, Domenico Ribatti
Vascular Stem Cells in Regulation of Angiogenesis / Jingwei Lu, Vincent J. Pompili, Hiranmoy Das
Toll-Like Receptor-Linked Signal Transduction in Angiogenesis / Karsten Grote, Harald Schütt, Bernhard Schieffer
Role of Sex Steroids in Angiogenesis / Laura Lecce, Yuen Ting Lam, Martin K. C. Ng
Biochemical Mechanisms of Exercise-Induced Angiogenesis / Dustin Scott Kehler, Naranjan S. Dhalla, Todd A. Duhamel
Pathophysiological Aspects of Angiogenesis. Angiogenesis in Atherosclerosis: An Overview / Sadip Pant, Abhishek Deshmukh, Jawahar L. Mehta
Role of Serotonin in Angiogenesis in Diabetes / Masaaki Iwabayashi ... [et al.]
Brain Angiogenesis After Stroke / Kazuhide Hayakawa ... [et al.]
Angiogenesis in Myocardial Ischemia / Yasuyuki Fujita, Takayuki Asahara, Atsuhiko Kawamoto
Adipose Tissue-Derived Mesenchymal Stem Cell and Angiogenesis in Ischemic Heart Disease / Lina Badimon, Blanca Oñate, Gemma Vilahur
Trials of Angiogenesis Therapy in Patients with Ischemic Heart Disease / Sandeep Singla, Jawahar L. Mehta
Angiogenesis in Cancer / Gerald W. Prager, Christoph C. Zielinski
Potential Mechanisms Linking Oxidized LDL to Susceptibility to Cancer / Magomed Khaidakov, Jawahar L. Mehta
Role of Genetic Polymorphisms in the Angiogenesis Pathway and Non-small-Cell Lung Cancer Tumor Behavior: Implications in Risk Assessment and Clinical Outcome / Ramon Andrade de Mello ... [et al.]
Pharmacology and Therapy of Angiogenesis. Angiogenic and Arteriogenic Factors: Their Role in the Treatment of Cancer and Arterial Regeneration / Wolfgang Schaper
Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis / Hiroyuki Ohnishi ... [et al.]
Harnessing Endothelial Progenitor Cells for Therapeutic Angiogenesis / Alan W. Stitt, Reinhold J. Medina
Microarray, MicroRNA, and Angiogenesis / Zufeng Ding, Xianwei Wang, Jawahar L. Mehta
MicroRNA and Cardiovascular Disorders with a Focus on Angiogenesis / Elena Cavarretta, Giacomo Frati, Gianluigi Condorelli
Overview of Angiogenesis Inhibitors from Natural Sources / Dipti Gatne, Veeranjaneyulu Addepalli.Digital Access Springer 2013 - ArticleOng KS, Grieco MH, Rosner W.J Allergy Clin Immunol. 1978 Aug;62(2):115-8.Triacetyloleandomycin (TAO) and its parent compound oleandomycin have a "steroid-sparing" effect in asthmatic patients. This study was designed to determine whether oleandomycin would enhance the inhibitory action of glucocorticosteroids in suppressing the blast transformation of phytohemagglutinin-stimulated human lymphocytes. Although oleandomycin could not be shown to inhibit the phytohemagglutinin stimulation of lymphocytes, there was a significant potentiation of steroid suppression at each concentration of methylprednisolone examined. This augmentation of glucocorticosteroid suppression of lymphocyte proliferation in vitro appears to support the clinically observed "steroid-sparing" effect of TAO and therefore its usefulness may not be limited to asthma and bronchitis.