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  A History of Modern Immunology : the Path Toward Understanding

  Zoltan A. Nagy.

  Summary: A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this history, the book gives insight into personal aspects of the important figures in the discipline, and its data driven emphasis on understanding will benefit both young and experienced scientists. This book provides a concise introduction to topics including immunological specificity, antibody diversity, monoclonal antibodies, major histocompatibility complex, antigen presentation, T cell biology, immunological tolerance, and autoimmune disease. This broad background of the discipline of immunology is a valuable companion for students of immunology, research and clinical immunologists, and research managers in the pharmaceutical and biotechnology industries. Contains the history of major breakthroughs in immunology featured with authenticity and insider detailsGives an insight into personal aspects of the players in the history of immunologyEnables the reader to recognize and select data of heuristic value which elucidate important facets of the immune systemProvides good examples and guidelines for the recognition and selection of what is important for the exploration of the immune systemGives clear separation of descriptive and interpretive parts, allowing the reader to distinguish between facts and analysis provided by the author.

  Digital Access ScienceDirect 2014
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• Article

  Immundefekte bei Leukämien und malignen Lymphomen als Ursache septischer Komplikationen. [Immune defects as a cause of septic complications in leukemias and malignant lymphomas (author's transl)].

  Hennemann HH.

  MMW Munch Med Wochenschr. 1978 Jun 30;120(26):891-4.

  Septicemias, especially those due to gram-negative pathogens, frequently occur in leukemias, malignant lymphomas and other malignant or metabolic diseases leading to inanition. The causes are disturbances of cellular defense and humoral immune defects. The immune reaction can be affected by disordered antibody function. In addition to a disturbance of leukocyte function due to reduction of granulocytes (granulocytopenia) disturbances of leukocyte function also occur with a normal cell count (granulocytopathy) especially under cytostatic therapy. Besides specific antibiotic therapy it is important to improve the defense position of the organism by treating the primary disease and to assess the disordered immune status correctly.

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  PubMed