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  • Book
    edited by Louis M. Weiss and Kami Kim.
    Summary: This book reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism.

    Contents:
    1. The history and life cycle of Toxoplasma gondii / J.P. Dubey
    2. The ultrastructure of Toxoplasma gondii / David J.P. Ferguson, Jean-Francois Dubremetz
    3. Molecular epidemiology and population structure of Toxoplasma gondii / Marie-Laure Darde, Daniel Ajzenberg, Chunlei Su
    4. Human Toxoplasma infection / Rima McLeod [and three others]
    5. Ocular disease due to Toxoplasma gondii / Emily Su, Andrea Honda, Paul Latkany
    6. Toxoplasmosis in wild and domestic animals / David S. Lindsay, J.P. Dubey
    7. Toxoplasma animal models and therapeutics / Carsten G.K. Luder, Utz Reichard, Uwe Gross
    8. Biochemistry and metabolism of Toxoplasma gondii : carbohydrates, lipids and nucleotides / Isabelle Coppens, Takashi Asai, Stanislas Tomavo
    9. The apicoplast and mitochondrion of Toxoplasma gondii / Frank Seeber, Jean E. Feagin, Marilyn Parsons
    10. Calcium storage and homeostasis in Toxoplasma gondii / Silvia N.J. Moreno, Lucas Borges Pereira, Douglas A. Pace
    11. The Toxoplasma gondii parasitophorous vacuole membrane : a multifunctional organelle in the infected cell / Anthony P. Sinai
    12. Toxoplasma secretory proteins and their roles in cell invasion and intracellular survival / Maryse Lebrun, Vern B. Carruthers, Marie-France Cesbron-Delauw
    13. The Toxoplasma cytoskeleton : structures, proteins and processes / Naomi Morrissette, Marc-Jan Gubbels
    14. Interactions between Toxoplasma effectors and host immune responses / Barbara A. Butcher [and three others]
    15. Bradyzoite development / Laura J. Knoll, Tadakimi Tomita, Louis M. Weiss
    16. Development and application of classical genetics in Toxoplasma gondii / James W. Ajioka, L. David Sibley
    17. Genetic manipulation of Toxoplasma gondii / Damien Jacot [and four others]
    18. Epigenetic and genetic factors that regulate gene expression in Toxoplasma gondii / William J. Sullivan, Jr. [and three others]
    19. ToxoDB : an integrated functional genomic resource for Toxoplasma and other sarcocystidae / Omar S. Harb, David S. Roos on behalf of the Eupathdb Group
    20. Comparative aspects of nucleotide and amino acid metabolism in Toxoplasma gondii and other apicomplexa / Kshitiz Chaudhary, Barbara A. Fox, David J. Bzik
    21. Toxoplasma gondii chemical biology / Matthew Bogyo, Gary Ward
    22. Proteomics of Toxoplasma gondii / Jonathan M. Wastling, Dong Xia
    23. Cerebral toxoplasmosis : pathogenesis, host resistance and behavioural consequences / Yasuhiro Suzuki [and five others]
    24. Innate immunity to Toxoplasma gondii / Dana G. Mordue, Christopher A. Hunter
    25. Adaptive immunity and genetics of the host immune response / Craig W. Roberts [and five others]
    26. Vaccination against toxoplasmosis : current status and future prospects / Craig W. Roberts [and three others].
    Digital Access ScienceDirect 2014
  • Article
    Macmanus Q, Grunkemeier G, Lambert L, Dietl C, Starr A.
    J Thorac Cardiovasc Surg. 1978 Jun;75(6):865-9.
    The results in 80 patients undergoing simultaneous aortic valve replacement and aorta-coronary saphenous vein bypass grafting were analyzed to assess the effect of operative technique. The over-all operative mortality rate of 6.3% (five of 80) did not differ significantly from our results with aortic valve replacement alone. All patients who had isolated aortic valve replacement were operated upon with moderate hypothermia. The combined operation was performed in two ways. Thirty-one patients had aortic valve replacement prior to bypass grafting with intermittent coronary ostila perfusion. There were two deaths (6.5%), and five myocardial infarctions (16.1%) were diagnosed by standard electrocardiographic and enzyme criteria. More recently, 49 patients have undergone bypass grafting prior to aortic valve replacement. The proximal ends of the grafts were either anastomosed high on the aortic root or else individually cannulated to provide continuous distal perfusion during subsequent aortic valve replacement, with continuous coronary ostial perfusion. There were three operative deaths (6.1%) and one myocardial infarction (2.0%). The risk of combined aortic valve replacement and coronary bypass need be no greater than the risk of aortic valve replacement alone. Our experience suggests that myocardial perfusion distal to significant coronary artery stenoses reduces the risk of myocardial infarction in patients with coronary artery disease requiring aortic valve replacement.
    Digital Access Access Options