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- BookJean A. Klastersky, Consultant, Medical Oncology, Institut Jules Bordet, Centre des Tumeurs de l'Universite Libre de Bruxelles, Brussels, Belgium.Contents:
1. Introduction
2. Prevention of febrile neutropenia
3. Prediction of the risk of complications associated with febrile neutropenia
4. Management of low-risk patients
5. Management of non-low-risk patients with febrile neutropenia
6. Management of persistent fever in patients with neutropenia despite empirical antibiotic administration
7. Costs associated with febrile neutropenia
8. At the extremes of age, febrile neutropenia in children and elderly - ArticleArala-Chaves MP, Hope L, Korn JH, Fudenberg H.Eur J Immunol. 1978 Feb;8(2):77-81.The roles of adherent and nonadherent T cells in the responses to phytohemagglutinin (PHA) and concanavalin A (Con A) were studied. [3H]thymidine uptake by mononuclear cells from human thymus and peripheral blood was used to measure the relative influence of monocytes and B cells on the responses to these mitogens. The response to Con A was dependent on two populations of T cells, one adherent to cotton or nylon and the other nonadherent. The first population appeared to potentiate the latter. In contrast, the response to PHA was dependent only on the nonadherent T cell subpopulation. The responses to PHA and to Con A were both dependent on monocytes to approximately the same extent, but the response to Con A, unlike the response to PHA, was also slightly dependent on B cells.