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  • Book
    Brendon J. Coventry, editor.
    Summary: Written by internationally acclaimed specialists, General Surgery Risk Reduction expands on complications associated with surgery and how to reduce them, the availability of relevant information and the rapid advancements of surgical technology. Chapters provide pertinent and concise procedure descriptions creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. Complications are reviewed when appropriate for the organ system and problem. The text is illustrated throughout by line drawings and photographs that depict anatomic or technical principles. Forming part of the series, Surgery: Complications, Risks and Consequences, this volume General Surgery Risk Reduction provides a valuable resource for all general surgeons and residents in training. Other healthcare providers will also find this a useful resource.

    Contents:
    1. Introduction
    2. General Peri-operative Complications
    3. Surgical Infection
    4. Pre-Operative Risk Assessment and Intra-Operative Monitoring
    5. Anaesthesia Complications
    6. Intensive Care Complications
    7. Acute Peri-Operative Pain: Mechanisms and Management
    8. Systems, Safety and Quality : Harm, Error and Litigation
    9. Risk Management and Human Factors
    10. Medico-Legal Risk Management in Surgery
    11. Evaluation of Surgical Safety and Efficacy
    12. Accreditation, Credentialing, Scope of Practice and Outcome Evaluation.
    Digital Access Springer 2014
  • Article
    Cook JD, Trotter JL, Engel WK, Sciabbarrasi JS.
    Ann Neurol. 1978 Feb;3(2):166-76.
    Several immunological variables were examined in patients receiving high-single-dose, alternate-day prednisone therapy for neuromuscular diseases. Dose-dependent leukocytosis, lymphopenia, and monocytopenia occurred which were maximal 6 hours after prednisone administration but returned to control levels by the 24-hour point. The lymphopenia involved T-cells, B-cells, and null cells, with the T-cells most affected. Plasma cortisol levels and lymphocyte transformation in response to mitogens were also transiently and reversibly suppressed. There was a persistent decrease in serum IgG. Lymphocyte transformation was also suppressed when normal lymphocytes were incubated with treated patient sera or when treated patient lymphocytes were incubated in autologous pretreatment sera. The suppression factor was not removed from the lymphocytes by extensive washing. Patients whose disease responded to the high-single-dose, alternate-day prednisone regiment were indistinguishable from nonresponders by the immunological responses measured.
    Digital Access Access Options