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  • Book
    Roger P. Harrie, Cynthia J. Kendall.
    Summary: The second editon of this popular ultrasound book expands the reader's understanding of the clinical applications of ocular ultrasound through a case study approach. With the addition of high-quality video segments of examination techniques not currently available in any other format, this edition appeals to a broader range of practitioners in the field by presenting the subject starting at the basic level and progressing to the advanced. The book is appealing to practitioners involved in ocular ultrasound, including ophthalmic technicians, ophthalmologists, optometrists, radiologists and emergency room physicians who, on occasion, are involved in the practice of ophthalmic ultrasound.
    Digital Access Springer 2014
  • Article
    Haaijman JJ, Hijmans W.
    Mech Ageing Dev. 1978 May;7(5):375-98.
    The immunological activity and capacity were studied in the CBA mouse as a function of its age. The activity was determined by the number of immunoglobulin containing (C-Ig) cells in different lymphoid organs and the immunoglobulin levels of the serum in non-artificially stimulated animals. It was confirmed that in older age the bone marrow takes over from the spleen the role of the major site of immunoglobulin production. A clear decrease in the number of C-Ig cells was observed in the mesenteric lymph nodes and the Peyer's patches. The Ig serum remained constant after the sixth month of age, with the exception of an increase of IgG1 and IgG,2B. There was a striking increase in variation between the individual animals with advancing age. From these data it can be concluded that the B-cell system of old animals is as active as that of young adult animals. The immunological capacity of CBA mice of various ages was assessed by measuring the levels of specific antibodies after the administration of human serum albumin in complete Freund's adjuvant. A severe decline of the primary and the secondary response was observed on ageing. The reaction of three year old animals was negligible. The discrepancy between the declining immunological capacity and the constant or increasing immunological activity is explained by an age-related deficiency of the T-cell compartment in the spleen.
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