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- BookKeith L. Moore, T.V.N. Persaud, Mark G. Torchia.Contents:
Introduction to the developing human
First week of human development
Second week of human development
Third week of human development
Fourth to eighth weeks of human development
Ninth week to birth: the fetal period
Placenta and fetal membranes
Body cavities and diaphragm
Pharyngeal apparatus, face, and neck
Respiratory system
Alimentary system
Urogenital system
Cardiovascular system
Skeletal system
Muscular system
Development of limbs
Nervous system
Development of eyes and ears
Integumentary system
Human birth defects
Common signaling pathways used during development. - ArticleBraciale TJ, Yap KL.J Exp Med. 1978 Apr 01;147(4):1236-52.This report examines the requirement for infectious virus in the induction of influenza virus-specific cytotoxic T cells. Infectious influenza virus was found to be highly efficient at generating both primary and secondary cytotoxic T-cell response in vivo. Inactivated influenza virus however, failed to stimulate a detectable cytotoxic T-cell response in vivo even at immunizing doses 10(5)-10(6)-fold higher than the minimum stimulatory dose of infectious virus. Likewise inactivated virus failed to sensitize target cells for T cell-mediated lysis in vitro but could stimulate a specific cytotoxic response from primed cells in vitro. Possible requirements for the induction of virus-specific cytotoxic T-cell responses are discussed in light of these observations and those of other investigators.