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  • Book
    S. Lochlann Jain.
    Summary: "Cancer can kill: this fact makes it concrete. Still, it's a devious knave. Nearly every American will experience it up-close and all too personally, wondering why the billions of research dollars thrown at the word haven't exterminated it from the English language. Like a sapper diffusing a bomb, Jain unscrambles the emotional, bureaucratic, medical, and scientific tropes that create the thing we call cancer. Scientists debate even the most basic facts about the disease, while endlessly generated, disputed, population data produce the appearance of knowledge. Jain takes the vacuum at the center of cancer seriously and demonstrates the need to understand cancer as a set of relationships--economic, sentimental, medical, personal, ethical, institutional, statistical. Malignant analyzes the peculiar authority of the socio-sexual psychopathologies of body parts; the uneven effects of expertise and power; the potentially cancerous consequences of medical procedures such as IVF; the huge industrial investments that manifest themselves as bone-cold testing rooms; the legal mess of medical malpractice law; and the teeth-grittingly jovial efforts to smear makeup and wigs over the whole messy problem of bodies spiraling into pain and decay. Malignant examines the painful cognitive dissonances produced by the ways a culture that has relished dazzling success in every conceivable arena have twisted one of its staunchest failures into an economic triumph. The intractable foil to American achievement, cancer hands us -- on a silver platter and ready for Jain's incisively original dissection -- our sacrifice to the American Dream"-- Provided by publisher.

    Contents:
    Introduction: We just don't know it yet
    Living in prognosis : the firing squad of statistics
    Poker face : gaming a lifespan
    Cancer butch : trip up the fast lane
    Lost chance : medical mistakes
    The mortality effect : the future in cancer trials
    Inconceivable : where IVF goes bad
    Can sir : what screening doesn't do
    Fallout : minuets in the key of fear
    Rubble : Bakelite bodies
    Conclusion: Shameless.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    2013
    RC276 .J35 2013
    1
  • Article
    Vértes M, Göcze P, Varga P, Kovács S.
    Endocrinol Exp. 1977 Dec;11(4):227-34.
    Specific binding of 3H-estradiol (1 microgram kg-1 injected s.c. 1 h before sacrifice) in the hypothalamus, anterior pituitary and uterus of cycling and ovariectomized female rats was investigated. Preoptic-anterior hypothalamic area (POA-AH) and median eminence-basal hypothalamus (ME-BH) were separated by gross dissection from the bulk of hypothalamus. Pieces of parietal cortex served as controls. The lowest amount of 3H-estradiol specifically bound to cytoplasmic and nuclear receptors in POA-AH and ME-BH was found in proestrus, while in estrus-metestrus it was the highest. In contrast to hypothalamic estrogen sensitive areas, the lowest uterine binding was found in estrus and the highest in diestrus-proestrus. Changes in estradiol binding in the anterior pituitary were similar to that in the uterus. Ovariectomy made 48 h before 3H-estradiol injection markedly increased the nuclear binding in POA-AH and ME-BH compared to that observed in cycling animals. However, it decreased nuclear binding in the uterus. Cytoplasmic binding seems to be decreased in the hypothalamus as well as in the uterus of ovariectomized animals as compared to the highest level observed during estrous cycle in intact ones.
    Digital Access Access Options