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  • Book
    Melina R. Kibbe, Scott A. LeMaire, editors.
    Summary: Academic surgeons play an essential role in advancing the field and improving the care of patients with surgical disease. As the Association for Academic Surgery (AAS) Fall Courses (www.aasurg.org) and international courses continue to evolve to address the rapidly expanding scope and complexity of academic surgery, there is a greater need for an accompanying textbook to supplement the material presented in the courses. Success in Academic Surgery: Basic Science is a unique and portable handbook that focuses on the basic and translational research. It includes new educational materials that are necessary to address not only the rapid evolution and rise of novel research methodologies in basic science and translational research, but also the changing environment for academic surgeons. Success in Academic Surgery: Basic Science is a valuable text for medical students, surgical residents, junior faculty and others considering a career in surgical research.

    Contents:
    How to set up, staff and fund your basic science or translational research laboratory
    Choosing a good basic science or translational research mentor
    Effective time management strategies
    How to read the literature, develop a hypothesis, and design an experiment for basic science and translational research
    Tips on maintaining an effective lab notebook for bench research
    How to conduct cell culture
    Modern techniques for protein assessment
    Modern techniques for DNA and RNA assessments
    Utilizing flow cytometry effectively
    Considerations for immunohistochemistry
    Stem cells: are they pertinent to my research?
    Use of genetically engineered mice for research
    Getting you IACUC proposal approved
    How to protect your intellectual property: invention disclosures and patents
    Statistics for bench research
    Ethics in laboratory research.
    Digital Access Springer 2014
  • Article
    Bedrick AD, Ladda RL.
    Teratology. 1978 Feb;17(1):13-8.
    Epidermal growth factor (EGF) injected into pregnant mice increased the frequency of cleft palate (CP) in cortisone-treated mouse fetuses. EGF alone produced proliferation and thickening of the epithelium of the palatal processes, but CP was not significantly increased over saline injected controls. Cortisone alone produced thinning of the palatal epithelium and caused CP in 61 percent of formed fetuses. The combination of EGF and cortisone treatment induced CP in 100 percent of formed fetuses; epithelial thickening still occurred with the combination treatment. Thus, EGF may be teratogenic under special circumstances. These observations suggest that the relative thickness of the palatal shelf epithelium may not be a critical factor in the fusion of the palatal shelves.
    Digital Access Access Options