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- ArticleLewis JC, Bowie FJ.Mayo Clin Proc. 1978 Mar;53(3):179-83.Platelets from normal pigs and pigs with von Willebrand's disease were studied by ultrastructural and scanning electron microscopy. The majority of resting platelets were discoid or abortive-dendritic in gross morphology with an average size of 2.6 micrometer. The number of alpha-granules per platelet section was varied; however, a highly significant positive association was found between platelet size and the number of alpha-granules. These studies characterize porcine platelets more definitively and clearly establish the similarities between platelets from normal and those from von Willebrand pigs.