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- ArticleWekerle H.J Exp Med. 1978 Jan 01;147(1):233-50.Immunological memory has been induced in vitro against testicular autoantigens by priming normal rat T lymphocytes against autologous testis cells, and by permitting the isolated blast cells to revert back to small secondary lymphocytes (secondary EAO cells) in the absence of the priming antigen. The secondary EAO cells vigorously respond in a secondary response when reconfronted with syngeneic testis or lymphoid cells. Their responsiveness to nonself stimulator cells is, however, reduced. Secondary cells derived from concanavalin A-stimulated blasts, do not show that pattern of specificity. The specificity of the secondary EAO cells is definite, and cannot be affected by further culture on allogeneic fibroblasts, which are antigenic for unprimed T lymphocytes. At least part of the autoantigens are determined by the major histocompatibility gene complex (MHC). Factors provided by the culture system do not appear to determine the specificity of this reaction. Only minor cell populations can restimulate secondary EAO cells. One of these populations is presumably phage-like cells within the lymphoid populations can elicit a secondary EAO response. Thus, the autoantigens relevant in the secondary EAO response are either MHC antigens restricted to these testicular and lymphoid subpopulations, or MHC antigens recognized in conjunction with organ-specific non-MHC determinants.
- BookNuclear medicine technology : review questions for the board examinations. Fourth edition. [4th ed.]Karen Ramer, Eleanor Mantel, Janet S. Reddin, Gang Cheng, Abass Alavi.Summary: This book prepares students and technologists for registry examinations in nuclear medicine technology by providing practice questions and answers with detailed explanations, as well as a mock registry exam.The questions are designed to test the basic knowledge required of nuclear medicine technologists, as well as the practical application of that knowledge.The topics covered closely follow the content specifications and the components of preparedness as published by the certification boards.This 4th edition includes expanded coverage of positron emission tomography and other new procedures and practices in the field of nuclear medicine and molecular imaging.
Contents:
Introduction
Radioactivity, Radiopharmacy, and Quality Assurance
Radiation Safety
Instrumentation and Quality Assurance
Image Presentation and Computers
Skeletal System Scintigraphy
Central Nervous System Scintigraphy
Cardiovascular System Scintigraphy
Respiratory System Scintigraphy
Gastrointestinal Tract Scintigraphy
Genitourinary System Scintigraphy
Oncologic Scintigraphy
Infection Scintigraphy
Thyroid, Parathyroid, and Salivary Gland Scintigraphy
Non-imaging Procedures and Radionuclide Therapy
Patient Care
Positron Emission Tomography
Multimodality Imaging
Mock Examination
Answers to Chapter 2
Answers to Chapter 3
Answers to Chapter 4
Answers to Chapter 5
Answers to Chapter 6
Answers to Chapter 7
Answers to Chapter 8
Answers to Chapter 9
Answers to Chapter 10
Answers to Chapter 11
Answers to Chapter 12
Answers to Chapter 13
Answers to Chapter 14
Answers to Chapter 15
Answers to Chapter 16
Answers to Chapter 17
Answers to Chapter 18
Mock Examination Answers.